Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF | R&D Systems 2840-A3 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF

catalog :

2840-A3

quantity :

50 ug

price :

419 USD

citations: 2

Reference
Koh K, Cao Y, Mangos S, Tardi N, Dande R, Lee H, et al. Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist. J Clin Invest. 2019;129:1713-1726 pubmed publisher
Haidari M, Zhang W, Caivano A, Chen Z, Ganjehei L, Mortazavi A, et al. Integrin ?2?1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells. J Biol Chem. 2012;287:32981-92 pubmed

product information

brand :

R&D Systems

master code :

2840-A3

SKU :

2840-A3-050

product name :

Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF

description :

The Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF has been validated for the following applications: Binding Activity.

target :

Integrin alpha 3 beta 1/VLA-3

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris-Citrate and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

150 kDa and 125 kDa, reducing conditions

theoretical molecular weight :

110.5 kDa (Integrin alpha 3), 82.3 kDa (Integrin beta 1)

gene symbol :

ITGA3

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Collagen IV at 10 µg/mL can bind rhIntegrin a3/beta 1 with an apparent Kd 2 nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

2840-A3

accessionNumbers :

P26006 (Integrin alpha 3) P05556 (Integrin beta 1)

applications :

Binding Activity

source :

Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha 3 beta 1/VLA-3 protein Human Integrin alpha 3 (Phe33-Glu991) Accession # P26006 acidic tail Human Integrin beta 1 (Glu21-Asp728) Accession # P05556 basic tail N-terminus C-terminus

2020 USD :

398

2021 USD :

419 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.