This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD5L Protein, CF
catalog :
2797-CL
quantity :
50 ug
price :
339 USD
citations: 3
Reference
Iannaccone A, Hollingsworth T, Koirala D, New D, Lenchik N, Beranova Giorgianni S, et al. Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration. Exp Eye Res. 2017;155:64-74 pubmed publisher
Amézaga N, Sanjurjo L, Julve J, Aran G, Pérez Cabezas B, Bastos Amador P, et al. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake. J Leukoc Biol. 2014;95:509-20 pubmed publisher
Gray J, Chattopadhyay D, Beale G, Patman G, Miele L, King B, et al. A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease. BMC Cancer. 2009;9:271 pubmed publisher
product information
brand :
R&D Systems
master code :
2797-CL
SKU :
2797-CL-050
product name :
Recombinant Human CD5L Protein, CF
description :
The Recombinant Human CD5L Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD5L Protein, CF has been validated for the following applications: Bioactivity.
target :
CD5L
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
43 kDa, reducing conditions
theoretical molecular weight :
36.9 kDa
gene symbol :
CD5L
details of functionality :
Measured by its ability to inhibit apoptosis on the J774A.1 mouse reticulum cell sarcoma macrophage cells. Miyazaki, T. et al . (1999) J. Exp. Med. 189 :413. The presence of rhCD5L inhibited rhFas Ligand induced apoptosis by 70-90%. The ED50 for this effect is 1-4 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
2797-CL
accessionNumbers :
O43866
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human CD5L protein Ser20-Gly347, with a C-terminal 6-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
AIM, API6, apoptosis inhibitor 6, CD5 antigen-like, CD5 antigen-like (scavenger receptor cysteine rich family), CD5 molecule-like, CD5L, CT-2, IgM-associated peptide, PRO229, Spalpha, SP-ALPHA
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.