Recombinant Human CD5L Protein, CF | R&D Systems 2797-CL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD5L Protein, CF

catalog :

2797-CL-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Watanabe Y, Fukuda T, Hayashi C, Nakao Y, Toyoda M, Kawakami K, et al. Extracellular vesicles derived from GMSCs stimulated with TNF-α and IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L expression. Sci Rep. 2022;12:13344 pubmed publisher
Lee J, Arumugarajah S, Lian D, Maehara N, Haig A, Suri R, et al. Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation. PLoS ONE. 2021;16:e0249838 pubmed publisher
Navas Madroñal M, Castelblanco E, Camacho M, Consegal M, Ramírez Morros A, Sarrias M, et al. Role of the Scavenger Receptor CD36 in Accelerated Diabetic Atherosclerosis. Int J Mol Sci. 2020;21: pubmed publisher
Iannaccone A, Hollingsworth T, Koirala D, New D, Lenchik N, Beranova Giorgianni S, et al. Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration. Exp Eye Res. 2017;155:64-74 pubmed publisher
Amézaga N, Sanjurjo L, Julve J, Aran G, Pérez Cabezas B, Bastos Amador P, et al. Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake. J Leukoc Biol. 2014;95:509-20 pubmed publisher
Gray J, Chattopadhyay D, Beale G, Patman G, Miele L, King B, et al. A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease. BMC Cancer. 2009;9:271 pubmed publisher

product information

brand :

R&D Systems

master code :

2797-CL

SKU :

2797-CL-050

product name :

Recombinant Human CD5L Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human CD5L Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD5L Protein, CF has been validated for the following applications: Bioactivity.

target :

CD5L

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

43 kDa, reducing conditions

theoretical molecular weight :

36.9 kDa

gene symbol :

CD5L

details of functionality :

Measured by its ability to inhibit apoptosis on the J774A.1 mouse reticulum cell sarcoma macrophage cells. Miyazaki, T. et al . (1999) J. Exp. Med. 189 :413. The presence of rhCD5L inhibited rhFas Ligand induced apoptosis by 70-90%. The ED50 for this effect is 1-4 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O43866

applications :

Bioactivity

source :

NS0-derived Recombinant Human CD5L Protein, CF

USD :

432 USD

alt names :

AIM, API6, apoptosis inhibitor 6, CD5 antigen-like, CD5 antigen-like (scavenger receptor cysteine rich family), CD5 molecule-like, CD5L, CT-2, IgM-associated peptide, PRO229, Spalpha, SP-ALPHA

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage