Recombinant Human CCL5/RANTES Protein | R&D Systems 278-RN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL5/RANTES Protein

catalog :

278-RN-010

quantity :

10 ug (also 50 ug)

price :

250 USD

more info or order :

R&D Systems product webpage

citations: 61

Reference
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Barroso González J, El Jaber Vazdekis N, García Expósito L, Machado J, Zarate R, Ravelo A, et al. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. J Biol Chem. 2009;284:16609-20 pubmed publisher
Eyman D, Damodarasamy M, Plymate S, Reed M. CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis. J Cell Physiol. 2009;220:376-81 pubmed publisher
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Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, et al. Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int J Cancer. 2008;122:769-76 pubmed
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product information

master code :

278-RN

SKU :

278-RN-010

product name :

Recombinant Human CCL5/RANTES Protein

unit size :

10 ug (also 50 ug)

description :

The Recombinant Human CCL5/RANTES Protein from R&D Systems is derived from E. coli.

target :

CCL5/RANTES

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

7.8 kDa

gene symbol :

CCL5

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. The ED50 for this effect is 1-5áng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human CCL5/RANTES Protein Bioactivity

accessionNumbers :

P13501

source long :

E. coli -derived human CCL5/RANTES protein Ser24-Ser91

source short :

E. coli

USD :

250 USD

alt names :

chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage