product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CCL5/RANTES Protein, CF
catalog :
278-RN-010/CF
quantity :
10 ug (also 50 ug)
price :
250 USD
more info or order :
citations: 60
Reference
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Barroso González J, El Jaber Vazdekis N, García Expósito L, Machado J, Zarate R, Ravelo A, et al. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. J Biol Chem. 2009;284:16609-20 pubmed publisher
Eyman D, Damodarasamy M, Plymate S, Reed M. CCL5 secreted by senescent aged fibroblasts induces proliferation of prostate epithelial cells and expression of genes that modulate angiogenesis. J Cell Physiol. 2009;220:376-81 pubmed publisher
Osei Kumah A, Smith R, Clifton V. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine. 2008;43:187-93 pubmed publisher
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Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, et al. Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Int J Cancer. 2008;122:769-76 pubmed
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Kish Catalone T, Pal R, Parrish J, Rose N, Hocker L, Hudacik L, et al. Evaluation of -2 RANTES vaginal microbicide formulations in a nonhuman primate simian/human immunodeficiency virus (SHIV) challenge model. AIDS Res Hum Retroviruses. 2007;23:33-42 pubmed
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product information
master code :
278-RN/CF
SKU :
278-RN-010/CF
product name :
Recombinant Human CCL5/RANTES Protein, CF
unit size :
10 ug (also 50 ug)
description :
The Recombinant Human CCL5/RANTES Protein, CF from R&D Systems is derived from E. coli.
target :
CCL5/RANTES
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
7.8 kDa
gene symbol :
CCL5
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. The ED50 for this effect is 1-5áng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human CCL5/RANTES Protein Bioactivity
accessionNumbers :
P13501
source long :
E. coli -derived human CCL5/RANTES protein Ser24-Ser91
source short :
E. coli
USD :
250 USD
alt names :
chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.