product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Lumican Protein, CF
catalog :
2745-LU-050
quantity :
50 ug
price :
447 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Cho H, Lee Y, Kim D, Moon S, Lee S, Lee S, et al. Lumican, an Exerkine, Protects against Skeletal Muscle Loss. Int J Mol Sci. 2022;23: pubmed publisher
Asega A, Menezes M, Trevisan Silva D, Cajado Carvalho D, Bertholim L, Oliveira A, et al. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases. Sci Rep. 2020;10:12912 pubmed publisher
Li X, Kang Y, Roife D, Lee Y, Pratt M, Perez M, et al. Prolonged exposure to extracellular lumican restrains pancreatic adenocarcinoma growth. Oncogene. 2017;36:5432-5438 pubmed publisher
Yu Y, Hoffhines A, Moore K, Leary J. Determination of the sites of tyrosine O-sulfation in peptides and proteins. Nat Methods. 2007;4:583-8 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
2745-LU
SKU :
2745-LU-050
product name :
Recombinant Mouse Lumican Protein, CF
Description :
The Recombinant Mouse Lumican Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Lumican Protein, CF has been validated for the following applications: Bioactivity.
target :
Lumican
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
observed molecular weight :
55-65 kDa, reducing conditions
theoretical molecular weight :
37.3 kDa
gene symbol :
Lum
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of BCE C/D-1b bovine corneal endothelial cells. When 5 x 104 cells per well are added to rmLumican coated plates (10 µg/mL, 100 µL/well) = 50% will adhere after 50 minutes at 37 °C. Optimal dilutions should be determined by each laboratory for each application. Also measured by its ability to modulate collagen fibrillogenesis.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P51885
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Lumican Protein
USD :
447 USD
alt names :
KSPG lumican, LDC, LUM, lumican, lumican proteoglycan, SLRR2D, SLRR2DLDCKeratan sulfate proteoglycan lumican
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.