Recombinant Human FGF-9 Protein | R&D Systems 273-F9 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-9 Protein

catalog :

273-F9

quantity :

25 ug

price :

259 USD

citations: 28

Reference
Asakawa M, Itoh M, Suganami T, Sakai T, Kanai S, Shirakawa I, et al. Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis. Sci Rep. 2019;9:19601 pubmed publisher
Bijland S, Thomson G, Euston M, Michail K, Thümmler K, Mücklisch S, et al. An in vitro model for studying CNS white matter: functional properties and experimental approaches. F1000Res. 2019;8:117 pubmed publisher
Murata H, Tsuzuki T, Kido T, Kakita Kobayashi M, Kida N, Hisamatsu Y, et al. Progestin-induced heart and neural crest derivatives-expressed transcript 2 inhibits angiopoietin 2 via fibroblast growth factor 9 in human endometrial stromal cells. Reprod Biol. 2019;19:14-21 pubmed publisher
Ho W, Freem L, Zhao D, Painter K, Woolley T, Gaffney E, et al. Feather arrays are patterned by interacting signalling and cell density waves. PLoS Biol. 2019;17:e3000132 pubmed publisher
Wu H, Uchimura K, Donnelly E, Kirita Y, Morris S, Humphreys B. Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics. Cell Stem Cell. 2018;23:869-881.e8 pubmed publisher
van den Berg C, Ritsma L, Avramut M, Wiersma L, van den Berg B, Leuning D, et al. Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo. Stem Cell Reports. 2018;10:751-765 pubmed publisher
Schutz L, Hurst R, Schreiber N, Spicer L. Transcriptome profiling of bovine ovarian theca cells treated with fibroblast growth factor 9. Domest Anim Endocrinol. 2018;63:48-58 pubmed publisher
Tumelty K, Higginson Scott N, Fan X, Bajaj P, Knowlton K, Shamashkin M, et al. Identification of direct negative cross-talk between the SLIT2 and bone morphogenetic protein-Gremlin signaling pathways. J Biol Chem. 2018;293:3039-3055 pubmed publisher
Taguchi A, Nishinakamura R. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells. Cell Stem Cell. 2017;21:730-746.e6 pubmed publisher
Doi R, Tsuchiya T, Mitsutake N, Nishimura S, Matsuu Matsuyama M, Nakazawa Y, et al. Transplantation of bioengineered rat lungs recellularized with endothelial and adipose-derived stromal cells. Sci Rep. 2017;7:8447 pubmed publisher
Glover J, Wells K, Matthäus F, Painter K, Ho W, Riddell J, et al. Hierarchical patterning modes orchestrate hair follicle morphogenesis. PLoS Biol. 2017;15:e2002117 pubmed publisher
Pode Shakked N, Gershon R, Tam G, Omer D, Gnatek Y, Kanter I, et al. Evidence of In Vitro Preservation of Human Nephrogenesis at the Single-Cell Level. Stem Cell Reports. 2017;9:279-291 pubmed publisher
El Agha E, Kheirollahi V, Moiseenko A, Seeger W, Bellusci S. Ex vivo analysis of the contribution of FGF10+ cells to airway smooth muscle cell formation during early lung development. Dev Dyn. 2017;246:531-538 pubmed publisher
Morizane R, Bonventre J. Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells. Nat Protoc. 2017;12:195-207 pubmed publisher
Totty M, Morrell B, Spicer L. Fibroblast growth factor 9 (FGF9) regulation of cyclin D1 and cyclin-dependent kinase-4 in ovarian granulosa and theca cells of cattle. Mol Cell Endocrinol. 2017;440:25-33 pubmed publisher
Tan G, Liang E, Liao K, Deng F, Zhang W, Chen Y, et al. NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-ÎºB subunit c-Rel in Paneth cell-like cells. Oncotarget. 2016;7:63651-63660 pubmed publisher
Yin H, Frontini M, Arpino J, Nong Z, O Neil C, Xu Y, et al. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases. J Biol Chem. 2015;290:22127-42 pubmed publisher
Sun C, Fukui H, Hara K, Zhang X, Kitayama Y, Eda H, et al. FGF9 from cancer-associated fibroblasts is a possible mediator of invasion and anti-apoptosis of gastric cancer cells. BMC Cancer. 2015;15:333 pubmed publisher
Meier F, Giesert F, Delic S, Faus Kessler T, Matheus F, Simeone A, et al. FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS ONE. 2014;9:e101124 pubmed publisher
Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers. J Am Soc Nephrol. 2014;25:1211-25 pubmed publisher
Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, et al. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell. 2014;14:53-67 pubmed publisher
Teishima J, Shoji K, Hayashi T, Miyamoto K, Ohara S, Matsubara A. Relationship between the localization of fibroblast growth factor 9 in prostate cancer cells and postoperative recurrence. Prostate Cancer Prostatic Dis. 2012;15:8-14 pubmed publisher
Frontini M, Nong Z, Gros R, Drangova M, O Neil C, Rahman M, et al. Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells. Nat Biotechnol. 2011;29:421-7 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher
Nakayama T, Mutsuga N, Tosato G. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood. 2007;109:1363-72 pubmed
Hendrix N, Wu R, Kuick R, Schwartz D, Fearon E, Cho K. Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas. Cancer Res. 2006;66:1354-62 pubmed
Cinaroglu A, Ozmen Y, Ozdemir A, Ozcan F, Ergorul C, Cayirlioglu P, et al. Expression and possible function of fibroblast growth factor 9 (FGF9) and its cognate receptors FGFR2 and FGFR3 in postnatal and adult retina. J Neurosci Res. 2005;79:329-39 pubmed
Schmahl J, Kim Y, Colvin J, Ornitz D, Capel B. Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development. 2004;131:3627-36 pubmed

product information

brand :

R&D Systems

master code :

273-F9

SKU :

273-F9-025

product name :

Recombinant Human FGF-9 Protein

description :

The Recombinant Human FGF-9 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human FGF-9 Protein has been validated for the following applications: Bioactivity.

target :

FGF-9

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4 and EDTA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

Multiple bands between 22-29 kDa, reducing conditions

theoretical molecular weight :

23 kDa

gene symbol :

FGF9

details of functionality :

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. Rubin, J.S. et al . (1991) Proc. Natl. Acad. Sci. USA 88 :415. The ED50 for this effect is 1-5 ng/mL.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

273-F9

accessionNumbers :

P31371

applications :

Bioactivity

source :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human FGF-9 protein Met1-Ser208 & Ala2-Ser208

2020 USD :

259

2021 USD :

259 USD

alt names :

FGF9, FGF-9, Fibroblast growth factor 9, fibroblast growth factor 9 (glia-activating factor), GAF, glia-activating factor, HBFG-9, HBGF-9, Heparin-binding growth factor 9, MGC119914, MGC119915, SYNS3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, 2 to 8 °C under sterile conditions after reconstitution.