Recombinant Human CD200 Fc Chimera Protein, CF | R&D Systems 2724-CD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD200 Fc Chimera Protein, CF

catalog :

2724-CD-050

quantity :

50 ug

price :

405 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Shafiei Jahani P, Helou D, Hurrell B, Howard E, Quach C, Painter J, et al. CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma. Nat Commun. 2021;12:2526 pubmed publisher
Blaeschke F, Willier S, Stenger D, Lepenies M, Horstmann M, Escherich G, et al. Leukemia-induced dysfunctional TIM-3+CD4+ bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients. Leukemia. 2020;34:2607-2620 pubmed publisher
Sun F, Zhang C, Chen X, Wei Y, Li S, Liu S, et al. Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. J Neuroinflammation. 2016;13:85 pubmed publisher

product information

brand :

R&D Systems

master code :

2724-CD

SKU :

2724-CD-050

product name :

Recombinant Human CD200 Fc Chimera Protein, CF

description :

The Recombinant Human CD200 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD200 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

CD200

category :

Proteins and Enzymes

unit sizes :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

70-75 kDa, reducing conditions

theoretical molecular weight :

49 kDa (monomer)

gene symbol :

CD200

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human CD200 R1 Fc Chimera (Catalog # 3414-CD ) is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Human CD200 Fc Chimera that produces 50% of the optimal binding response is appoximately 2.5-15 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P41217

applications :

Binding Activity

source :

NS0-derived Recombinant Human CD200 Fc Chimera Protein, CF

USD :

405 USD

alt names :

antigen identified by monoclonal MRC OX-2, CD200, CD200 antigenMOX1, CD200 molecule, MOX1, MOX2, MOX2MRC, MRC, MRC OX-2 antigen, OX-2, OX-2 membrane glycoprotein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage