Recombinant Human CD200 Fc Chimera Protein, CF | R&D Systems 2724-CD-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD200 Fc Chimera Protein, CF

catalog :

2724-CD-050

quantity :

50 ug

price :

443 USD

citations: 4

Reference
Sabogal Gu xe1 queta A, Marmolejo Garza A, Trombetta Lima M, Oun A, Hunneman J, Chen T, et al. Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction. Nat Commun. 2023;14:6454 pubmed publisher
Shafiei Jahani P, Helou D, Hurrell B, Howard E, Quach C, Painter J, et al. CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma. Nat Commun. 2021;12:2526 pubmed publisher
Blaeschke F, Willier S, Stenger D, Lepenies M, Horstmann M, Escherich G, et al. Leukemia-induced dysfunctional TIM-3+CD4+ bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients. Leukemia. 2020;34:2607-2620 pubmed publisher
Sun F, Zhang C, Chen X, Wei Y, Li S, Liu S, et al. Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. J Neuroinflammation. 2016;13:85 pubmed publisher

product information

master code :

2724-CD

SKU :

2724-CD-050

product name :

Recombinant Human CD200 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human CD200 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD200 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

CD200

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

70-75 kDa, reducing conditions

theoretical molecular weight :

49 kDa (monomer)

gene symbol :

CD200

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human CD200 R1 Fc Chimera (Catalog # 3414-CD ) is immobilized at 2 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human CD200 Fc Chimera that produces 50% of the optimal binding response is appoximately 2.5-15 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P41217

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human CD200 protein Human CD200 (Gln31-Gly232) Accession # P41217 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

443 USD

alt names :

antigen identified by monoclonal MRC OX-2, CD200, CD200 antigenMOX1, CD200 molecule, MOX1, MOX2, MOX2MRC, MRC, MRC OX-2 antigen, OX-2, OX-2 membrane glycoprotein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.