Recombinant Human Airway Trypsin-like Protease/HAT, CF | R&D Systems 2695-SE product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Airway Trypsin-like Protease/HAT, CF

catalog :

2695-SE

quantity :

10 ug

price :

309 USD

citations: 3

Reference
Straus M, Whittaker G. A peptide-based approach to evaluate the adaptability of influenza A virus to humans based on its hemagglutinin proteolytic cleavage site. PLoS ONE. 2017;12:e0174827 pubmed publisher
Heurich A, Hofmann Winkler H, Gierer S, Liepold T, Jahn O, Pohlmann S. TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein. J Virol. 2014;88:1293-307 pubmed publisher
Nygaard R, Golden J, Schiff L. Impact of host proteases on reovirus infection in the respiratory tract. J Virol. 2012;86:1238-43 pubmed publisher

product information

brand :

R&D Systems

master code :

2695-SE

SKU :

2695-SE-010

product name :

Recombinant Human Airway Trypsin-like Protease/HAT, CF

description :

The Recombinant Human Airway Trypsin-like Protease/HAT, CF from R&D Systems is derived from NS0. The Recombinant Human Airway Trypsin-like Protease/HAT, CF has been validated for the following applications: Enzyme Activity.

target :

Airway Trypsin-like Protease/HAT/TMPRSS11D

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

27 kDa and 18 kDa, reducing conditions

theoretical molecular weight :

25 kDa 17 kDa

gene symbol :

TMPRSS11D

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, t-butoxycarbonyl-Phe-Ser-Arg-7-amino-4-methyl coumarin (Boc-FSR-AMC). The specific activity is 50,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

2695-SE

accessionNumbers :

O60235

applications :

Enzyme Activity

source :

Mouse myeloma cell line, NS0-derived human Airway Trypsin-like Protease/HAT protein Ala42-Ile418 with an N-terminal 6-His tag The protein was purified, activated and further purified.

2020 USD :

309

2021 USD :

309 USD

alt names :

airway trypsin like protease, Airway trypsin-like protease, EC 3.4.21, EC 3.4.21.-, HAT, MGC150587, MGC150588, TMPRSS11D, transmembrane protease serine 11D, transmembrane protease, serine 11D

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.