Recombinant Human NT-4 Protein | R&D Systems 268-N4-005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human NT-4 Protein

catalog :

268-N4-005

quantity :

5 ug (also 25 ug)

price :

280 USD

citations: 10

Reference
Rahimov F, Nieminen P, Kumari P, Juuri E, Nikopensius T, Paraiso K, et al. High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene. Nat Commun. 2024;15:9568 pubmed publisher
Tian Y, Wang W, Lautrup S, Zhao H, Li X, Law P, et al. WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome. Nat Commun. 2022;13:5456 pubmed publisher
Segelcke D, Fischer H, Hütte M, Dennerlein S, Benseler F, Brose N, et al. Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice. Cell Rep. 2021;37:110152 pubmed publisher
Prautsch K, Schmidt A, Paradiso V, Schaefer D, Guzman R, Kalbermatten D, et al. Modulation of Human Adipose Stem Cells' Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro. Cells. 2020;9: pubmed publisher
Michel N, Narayanan P, Shomroni O, Schmidt M. Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction. Cell Rep. 2020;32:107912 pubmed publisher
Teotia P, Niu M, Ahmad I. Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single-cell transcriptome analysis. Stem Cells. 2020;38:1279-1291 pubmed publisher
Dabkowska M, Rogińska D, Kłos P, Sobuś A, Adamczak M, Litwińska Z, et al. Electrostatic complex of neurotrophin 4 with dendrimer nanoparticles: controlled release of protein in vitro and in vivo. Int J Nanomedicine. 2019;14:6117-6131 pubmed publisher
Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol. 2008;151:476-86 pubmed publisher
Royo N, Lebold D, Magge S, Chen I, Hauspurg A, Cohen A, et al. Neurotrophin-mediated neuroprotection of hippocampal neurons following traumatic brain injury is not associated with acute recovery of hippocampal function. Neuroscience. 2007;148:359-70 pubmed
Getmanova E, Chen Y, Bloom L, Gokemeijer J, Shamah S, Warikoo V, et al. Antagonists to human and mouse vascular endothelial growth factor receptor 2 generated by directed protein evolution in vitro. Chem Biol. 2006;13:549-56 pubmed

product information

master code :

268-N4

SKU :

268-N4-005

product name :

Recombinant Human NT-4 Protein

unit size :

5 ug (also 25 ug)

description :

The Recombinant Human NT-4 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human NT-4 Protein has been validated for the following applications: Bioactivity.

target :

NT-4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

14 kDa

gene symbol :

NTF4

details of functionality :

Measured in a cell proliferation assay using BaF mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.3-3 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P34130

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human NT-4 protein Gly81-Ala210

source short :

Sf 21 (baculovirus)

USD :

280 USD

alt names :

GLC10, GLC1O, neurotrophic factor 4, neurotrophic factor 5, neurotrophin 4, neurotrophin 5 (neurotrophin 4/5), neurotrophin-4, neurotrophin-5, Neutrophic factor 4, NT4, NT-4, NT-4/5, NT-5, NTF4, NTF5, NTF5NT5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.