Recombinant Human NT-4 Protein | R&D Systems 268-N4-005 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human NT-4 Protein

catalog :

268-N4-005

quantity :

5 ug (also 25 ug)

price :

273 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Tian Y, Wang W, Lautrup S, Zhao H, Li X, Law P, et al. WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome. Nat Commun. 2022;13:5456 pubmed publisher
Segelcke D, Fischer H, Hütte M, Dennerlein S, Benseler F, Brose N, et al. Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice. Cell Rep. 2021;37:110152 pubmed publisher
Prautsch K, Schmidt A, Paradiso V, Schaefer D, Guzman R, Kalbermatten D, et al. Modulation of Human Adipose Stem Cells' Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro. Cells. 2020;9: pubmed publisher
Michel N, Narayanan P, Shomroni O, Schmidt M. Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction. Cell Rep. 2020;32:107912 pubmed publisher
Teotia P, Niu M, Ahmad I. Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single-cell transcriptome analysis. Stem Cells. 2020;38:1279-1291 pubmed publisher
Dabkowska M, Rogińska D, Kłos P, Sobuś A, Adamczak M, Litwińska Z, et al. Electrostatic complex of neurotrophin 4 with dendrimer nanoparticles: controlled release of protein in vitro and in vivo. Int J Nanomedicine. 2019;14:6117-6131 pubmed publisher
Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol. 2008;151:476-86 pubmed publisher
Royo N, Lebold D, Magge S, Chen I, Hauspurg A, Cohen A, et al. Neurotrophin-mediated neuroprotection of hippocampal neurons following traumatic brain injury is not associated with acute recovery of hippocampal function. Neuroscience. 2007;148:359-70 pubmed
Getmanova E, Chen Y, Bloom L, Gokemeijer J, Shamah S, Warikoo V, et al. Antagonists to human and mouse vascular endothelial growth factor receptor 2 generated by directed protein evolution in vitro. Chem Biol. 2006;13:549-56 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

268-N4

SKU :

268-N4-005

product name :

Recombinant Human NT-4 Protein

Description :

The Recombinant Human NT-4 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human NT-4 Protein has been validated for the following applications: Bioactivity.

target :

NT-4

category :

Proteins and Enzymes

unit size :

5 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

14 kDa

gene symbol :

NTF4

details of functionality :

Measured in a cell proliferation assay using BaF mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.3-3 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P34130

applications :

Bioactivity

source :

Sf 21 (baculovirus)-derived Recombinant Human NT-4 Protein

USD :

273 USD

alt names :

GLC10, GLC1O, neurotrophic factor 4, neurotrophic factor 5, neurotrophin 4, neurotrophin 5 (neurotrophin 4/5), neurotrophin-4, neurotrophin-5, Neutrophic factor 4, NT4, NT-4, NT-4/5, NT-5, NTF4, NTF5, NTF5NT5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage