product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Angiogenin Protein
catalog :
265-AN-050
quantity :
50 ug (also 250 ug)
price :
525 USD
more info or order :
R&D Systems product webpage
citations: 10
Reference
Akiyama Y, Takenaka Y, Kasahara T, Abe T, Tomioka Y, Ivanov P. RTCB Complex Regulates Stress-Induced tRNA Cleavage. Int J Mol Sci. 2022;23: pubmed publisher
Liu X, Chai Y, Liu G, Su W, Guo Q, Lv X, et al. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. 2021;12:1832 pubmed publisher
Jeong J, Lee S, Ko K, Lee J, Lyu J, Park M, et al. Plant-derived angiogenin fusion protein's cytoprotective effect on trabecular meshwork damage induced by Benzalkonium chloride in mice. Peerj. 2020;8:e9084 pubmed publisher
Aluri K, Salisbury J, Prehn J, Agar J. Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration. Sci Rep. 2020;10:3715 pubmed publisher
Rütti S, Dusaulcy R, Hansen J, Howald C, Dermitzakis E, Pedersen B, et al. Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines. Sci Rep. 2018;8:10072 pubmed publisher
Crivello M, O Riordan S, Woods I, Cannon S, Halang L, Coughlan K, et al. Pleiotropic activity of systemically delivered angiogenin in the SOD1G93A mouse model. Neuropharmacology. 2018;133:503-511 pubmed publisher
Saikia M, Jobava R, Parisien M, Putnam A, Krokowski D, Gao X, et al. Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress. Mol Cell Biol. 2014;34:2450-63 pubmed publisher
Welch Reardon K, Ehsan S, Wang K, Wu N, Newman A, Romero Lopez M, et al. Angiogenic sprouting is regulated by endothelial cell expression of Slug. J Cell Sci. 2014;127:2017-28 pubmed publisher
Aad P, Echternkamp S, Sypherd D, Schreiber N, Spicer L. The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems. Biol Reprod. 2012;87:79 pubmed publisher
Schwartz B, Shoseyov O, Melnikova V, McCarty M, Leslie M, Roiz L, et al. ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis. Cancer Res. 2007;67:5258-66 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
265-AN
SKU :
265-AN-050
product name :
Recombinant Human Angiogenin Protein
Description :
The Recombinant Human Angiogenin Protein from R&D Systems is derived from E. coli. The Recombinant Human Angiogenin Protein has been validated for the following applications: Bioactivity.
target :
Angiogenin
category :
Proteins and Enzymes
unit size :
50 ug (also 250 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
14 kDa, reducing conditions
theoretical molecular weight :
14 kDa
gene symbol :
ANG
details of functionality :
Measured by its ribonucleolytic activity toward yeast tRNA. Lee and Vallee (1989) Biochem. Biophys. Res. Commun. 161 :121. Angiogenin produces a delta Abs260/µg 1.0 in two hours, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q53X86
applications :
Bioactivity
source :
E. coli-derived Recombinant Human Angiogenin Protein
USD :
525 USD
alt names :
ALS9, ANG, angiogenin, angiogenin, ribonuclease, RNase A family, 5, EC 3.1.27, EC 3.1.27.-, epididymis luminal protein 168, HEL168, MGC22466, MGC71966, Ribonuclease 5, RNase 5, RNASE5RNASE4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.