Recombinant Human Angiogenin Protein, CF | R&D Systems 265-AN-050/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Angiogenin Protein, CF

catalog :

265-AN-050/CF

quantity :

50 ug (also 250 ug)

price :

541 USD

citations: 10

Reference
Akiyama Y, Takenaka Y, Kasahara T, Abe T, Tomioka Y, Ivanov P. RTCB Complex Regulates Stress-Induced tRNA Cleavage. Int J Mol Sci. 2022;23: pubmed publisher
Liu X, Chai Y, Liu G, Su W, Guo Q, Lv X, et al. Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis. Nat Commun. 2021;12:1832 pubmed publisher
Jeong J, Lee S, Ko K, Lee J, Lyu J, Park M, et al. Plant-derived angiogenin fusion protein's cytoprotective effect on trabecular meshwork damage induced by Benzalkonium chloride in mice. Peerj. 2020;8:e9084 pubmed publisher
Aluri K, Salisbury J, Prehn J, Agar J. Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration. Sci Rep. 2020;10:3715 pubmed publisher
Rütti S, Dusaulcy R, Hansen J, Howald C, Dermitzakis E, Pedersen B, et al. Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines. Sci Rep. 2018;8:10072 pubmed publisher
Crivello M, O Riordan S, Woods I, Cannon S, Halang L, Coughlan K, et al. Pleiotropic activity of systemically delivered angiogenin in the SOD1G93A mouse model. Neuropharmacology. 2018;133:503-511 pubmed publisher
Saikia M, Jobava R, Parisien M, Putnam A, Krokowski D, Gao X, et al. Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress. Mol Cell Biol. 2014;34:2450-63 pubmed publisher
Welch Reardon K, Ehsan S, Wang K, Wu N, Newman A, Romero Lopez M, et al. Angiogenic sprouting is regulated by endothelial cell expression of Slug. J Cell Sci. 2014;127:2017-28 pubmed publisher
Aad P, Echternkamp S, Sypherd D, Schreiber N, Spicer L. The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems. Biol Reprod. 2012;87:79 pubmed publisher
Schwartz B, Shoseyov O, Melnikova V, McCarty M, Leslie M, Roiz L, et al. ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis. Cancer Res. 2007;67:5258-66 pubmed

product information

master code :

265-AN/CF

SKU :

265-AN-050/CF

product name :

Recombinant Human Angiogenin Protein, CF

unit size :

50 ug (also 250 ug)

description :

The Recombinant Human Angiogenin Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Angiogenin Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Angiogenin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

14 kDa, reducing conditions

theoretical molecular weight :

14 kDa

gene symbol :

ANG

details of functionality :

Measured by its ribonucleolytic activity toward yeast tRNA. Lee and Vallee (1989) Biochem. Biophys. Res. Commun. 161 :121. Angiogenin produces a delta Abs260/╡g 1.0 in two hours, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q53X86

applications :

Enzyme Activity

source long :

E. coli -derived human Angiogenin protein Gln25-Pro147

source short :

E. coli

USD :

541 USD

alt names :

ALS9, ANG, angiogenin, angiogenin, ribonuclease, RNase A family, 5, EC 3.1.27, EC 3.1.27.-, epididymis luminal protein 168, HEL168, MGC22466, MGC71966, Ribonuclease 5, RNase 5, RNASE5RNASE4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.