Recombinant Mouse Chitinase 3-like 1/YKL-40 Protein, CF | R&D Systems 2649-CH-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Chitinase 3-like 1/YKL-40 Protein, CF

catalog :

2649-CH-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Matute Blanch C, Calvo Barreiro L, Carballo Carbajal I, Gonzalo R, Sanchez A, Vila M, et al. Chitinase 3-like 1 is neurotoxic in primary cultured neurons. Sci Rep. 2020;10:7118 pubmed publisher
Lee C, He C, Nour A, Zhou Y, Ma B, Park J, et al. IL-13R?2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses. Nat Commun. 2016;7:12752 pubmed publisher
Tanaka Y, Matsumoto I, Inoue A, Umeda N, Takai C, Sumida T. Antigen-specific over-expression of human cartilage glycoprotein 39 on CD4+ CD25+ forkhead box protein 3+ regulatory T cells in the generation of glucose-6-phosphate isomerase-induced arthritis. Clin Exp Immunol. 2014;177:419-27 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2649-CH

SKU :

2649-CH-050

product name :

Recombinant Mouse Chitinase 3-like 1/YKL-40 Protein, CF

Description :

The Recombinant Mouse Chitinase 3-like 1/YKL-40 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Chitinase 3-like 1/YKL-40 Protein, CF has been validated for the following applications: Bioactivity.

target :

Chitinase 3-like 1/YKL-40

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

41 kDa, reducing conditions

theoretical molecular weight :

41.6 kDa

gene symbol :

Chil1

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of FaDu human squamous cell carcinoma cells. When 5 x 104 cells per well are added to rmCHI3-L1 coated plate, cell adhesion is enhanced in a dose dependent manner after 30 minutes at 37 °C. The ED50 for this effect is 0.8-3.2 µg/mL. . Optimal concentrations should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q61362

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse Chitinase 3-like 1/YKL-40 Protein

USD :

447 USD

alt names :

AW208766, Brp39, Chi3l1, Chitinase 3 like 1, gp39, HCgp39, YKL-40

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage