Recombinant Human Kallikrein 14 Protein, CF | R&D Systems 2626-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Kallikrein 14 Protein, CF

catalog :

2626-SE-010

quantity :

10 ug

price :

541 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Fischer J, Koblyakova Y, Latendorf T, Wu Z, Meyer Hoffert U. Cross-linking of SPINK6 by transglutaminases protects from epidermal proteases. J Invest Dermatol. 2013;133:1170-7 pubmed publisher
Fortugno P, Bresciani A, Paolini C, Pazzagli C, El Hachem M, D Alessio M, et al. Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis. J Invest Dermatol. 2011;131:2223-32 pubmed publisher
Kantyka T, Fischer J, Wu Z, Declercq W, Reiss K, Schroder J, et al. Inhibition of kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6. Peptides. 2011;32:1187-92 pubmed publisher
Meyer Hoffert U, Wu Z, Kantyka T, Fischer J, Latendorf T, Hansmann B, et al. Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related peptidases. J Biol Chem. 2010;285:32174-81 pubmed publisher
Sexton D, Chen T, Martik D, Kuzmic P, Kuang G, Chen J, et al. Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases. Biochem J. 2009;422:383-92 pubmed publisher
Yoon H, Laxmikanthan G, Lee J, Blaber S, Rodriguez A, Kogot J, et al. Activation profiles and regulatory cascades of the human kallikrein-related peptidases. J Biol Chem. 2007;282:31852-64 pubmed

image

image 1 :

Recombinant Human Kallikrein 14 Protein Enzyme Activity

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

2626-SE

SKU :

2626-SE-010

product name :

Recombinant Human Kallikrein 14 Protein, CF

description :

The Recombinant Human Kallikrein 14 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Kallikrein 14 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Kallikrein 14

unit size :

10 ug

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

observed molecular weight :

28 kDa, reducing conditions

theoretical molecular weight :

26 kDa

gene symbol :

KLK14

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC (Catalog # ES011 ). The specific activity is 3,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAD50773

applications :

Enzyme Activity

product keywords :

2626-SE, rhKLK14, hKLK14, carrier-free, carrier free, 2626SE, KLK 14, Kallikrein14, K14, Serine Protease, Tissue Kallikrein, Cancer Marker

source :

NS0-derived Recombinant Human Kallikrein 14 Protein, CF

USD :

525

USD 2025 :

541 USD

alt names :

EC 3.4.21, EC 3.4.21.-, hK14, kallikrein 14, Kallikrein-like protein 6, kallikrein-related peptidase 14, KLK14, KLKL6, KLK-L6kallikrein-14

more info or order :

R&D Systems product webpage