Recombinant Human HAPLN1 Protein, CF | R&D Systems 2608-HP-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human HAPLN1 Protein, CF

catalog :

2608-HP-025

quantity :

25 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Wiedmann L, De Angelis Rigotti F, Vaquero Siguero N, Donato E, Espinet E, Moll I, et al. HAPLN1 potentiates peritoneal metastasis in pancreatic cancer. Nat Commun. 2023;14:2353 pubmed publisher
Ecker B, Kaur A, Douglass S, Webster M, Almeida F, Marino G, et al. Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. Cancer Discov. 2019;9:82-95 pubmed publisher
Huynh M, Pak C, Markovina S, Callander N, Chng K, Wuerzberger Davis S, et al. Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma. J Biol Chem. 2018;293:2452-2465 pubmed publisher
Ivanova A, Goparaju C, Ivanov S, Nonaka D, Cruz C, Beck A, et al. Protumorigenic role of HAPLN1 and its IgV domain in malignant pleural mesothelioma. Clin Cancer Res. 2009;15:2602-11 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2608-HP

SKU :

2608-HP-025

product name :

Recombinant Human HAPLN1 Protein, CF

Description :

The Recombinant Human HAPLN1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human HAPLN1 Protein, CF has been validated for the following applications: Binding Activity.

target :

HAPLN1

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

45-52 kDa, reducing conditions

theoretical molecular weight :

39.8 kDa

gene symbol :

HAPLN1

details of functionality :

Measured by its ability to bind biotinylated hyaluronan in a functional ELISA.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P10915

applications :

Binding Activity

source :

NS0-derived Recombinant Human HAPLN1 Protein

USD :

423 USD

alt names :

Cartilage link protein, Cartilage-link protein, Cartilage-linking protein 1, CRTL1, CRTL1cartilage linking protein 1, hyaluronan and proteoglycan link protein 1, Proteoglycan link protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage