Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF | R&D Systems 2599-CH-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF

catalog :

2599-CH-050

quantity :

50 ug

price :

432 USD

citations: 6

Reference
Wang Y, Lin C, Huang M, Fang X, Chen G, Ye S. Overexpression of YKL40,IL-6, IL-8, TNF-α in tonsils and the role of YKL40 in childhood with obstructive sleep apnea syndrome. Sci Rep. 2024;14:26283 pubmed publisher
Yamanaka K, Koma Y, Urakami S, Takahashi R, Nagamata S, Omori M, et al. YKL40/Integrin β4 Axis Induced by the Interaction between Cancer Cells and Tumor-Associated Macrophages Is Involved in the Progression of High-Grade Serous Ovarian Carcinoma. Int J Mol Sci. 2024;25: pubmed publisher
Song Y, Jiang W, Afridi S, Wang T, Zhu F, Xu H, et al. Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus. Cell Rep. 2024;43:114226 pubmed publisher
Jiang W, Zhu F, Xu H, Xu L, Li H, Yang X, et al. CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation. Sci Adv. 2023;9:eadg8148 pubmed publisher
Starossom S, Campo Garcia J, Woelfle T, Romero Suarez S, Olah M, Watanabe F, et al. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nat Commun. 2019;10:217 pubmed publisher
Park J, Drazen J, Tschumperlin D. The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J Biol Chem. 2010;285:29817-25 pubmed publisher

product information

master code :

2599-CH

SKU :

2599-CH-050

product name :

Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF has been validated for the following applications: Bioactivity.

target :

Chitinase 3-like 1/YKL-40

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

38-41 kDa, reducing conditions

theoretical molecular weight :

41.3 kDa (monomer)

gene symbol :

CHI3L1

details of functionality :

Bioassay data are not available.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P36222

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Chitinase 3-like 1/YKL-40 protein Tyr22-Thr383, with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

AW208766, Brp39, Chi3l1, Chitinase 3 like 1, gp39, HCgp39, YKL-40

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.