Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF | R&D Systems 2599-CH-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF

catalog :

2599-CH-050

quantity :

50 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Starossom S, Campo Garcia J, Woelfle T, Romero Suarez S, Olah M, Watanabe F, et al. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nat Commun. 2019;10:217 pubmed publisher
Park J, Drazen J, Tschumperlin D. The chitinase-like protein YKL-40 is secreted by airway epithelial cells at base line and in response to compressive mechanical stress. J Biol Chem. 2010;285:29817-25 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2599-CH

SKU :

2599-CH-050

product name :

Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF

Description :

The Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Chitinase 3-like 1/YKL-40 Protein, CF has been validated for the following applications: Bioactivity.

target :

Chitinase 3-like 1/YKL-40

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

38-41 kDa, reducing conditions

theoretical molecular weight :

41.3 kDa (monomer)

gene symbol :

CHI3L1

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of FaDu human squamous cell carcinoma cells. When 5 x 104 cells per well are added to recombinant human CHI3-L1 coated plate, cell adhesion is enhanced in a dose dependent manner. The ED50 for this effect is 0.6-2.4 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P36222

applications :

Bioactivity

source :

NS0-derived Recombinant Human Chitinase 3-like 1/YKL-40 Protein

USD :

423 USD

alt names :

AW208766, Brp39, Chi3l1, Chitinase 3 like 1, gp39, HCgp39, YKL-40

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage