Recombinant Human Artemin Protein, CF | R&D Systems 2589-AR-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Artemin Protein, CF

catalog :

2589-AR-025/CF

quantity :

25 ug

price :

349 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, et al. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. Cell. 2018;173:634-648.e12 pubmed publisher
Luo Y, Tsuchiya K, Il Park D, Fausel R, Kanngurn S, Welcsh P, et al. RET is a potential tumor suppressor gene in colorectal cancer. Oncogene. 2013;32:2037-47 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher
Lu B, PereiraPerrin M. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun. 2008;76:3530-8 pubmed publisher

product information

brand :

R&D Systems

master code :

2589-AR/CF

SKU :

2589-AR-025/CF

product name :

Recombinant Human Artemin Protein, CF

description :

The Artemin Protein from 2589-AR-025/CF is derived from E. coli-derived Recombinant Human Artemin Protein. The Artemin Protein has been validated for the following applications: NP_476432.

target :

Artemin

category :

Proteins and Enzymes

unit sizes :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in HCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

12 kDa, reducing conditions

theoretical molecular weight :

12 kDa (monomer)

gene symbol :

ARTN

details of functionality :

Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is 4-16 ng/mL. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFR alpha-3/GDNF R alpha-3 Fc Chimera (Catalog # 7269-FR ) at 1 µg/mL (100 µL/well) can bind Recombinant Human Artemin with an apparent Kd 1 nM.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_476432

applications :

Bioactivity, Binding Activity

source :

E. coli-derived Recombinant Human Artemin Protein

USD :

349 USD

alt names :

artemin, ARTN, ENOVIN, EVN, EVNneurotrophic factor, NBN, Neublastin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage