Recombinant Mouse MMR/CD206 Protein, CF | R&D Systems 2535-MM-050/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse MMR/CD206 Protein, CF

catalog :

2535-MM-050/CF

quantity :

50 ug

price :

525 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Mooney B, Torres Velez F, Doering J, Ehrbar D, Mantis N. Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin-Ab complexes. J Leukoc Biol. 2019;106:1161-1176 pubmed publisher
Shibaguchi K, Tamura A, Terauchi M, Matsumura M, Miura H, Yui N. Mannosylated Polyrotaxanes for Increasing Cellular Uptake Efficiency in Macrophages through Receptor-Mediated Endocytosis. Molecules. 2019;24: pubmed publisher
Subramanian K, Neill D, Malak H, Spelmink L, Khandaker S, Dalla Libera Marchiori G, et al. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nat Microbiol. 2019;4:62-70 pubmed publisher
Scodeller P, Simón Gracia L, Kopanchuk S, Tobi A, Kilk K, Säälik P, et al. Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide. Sci Rep. 2017;7:14655 pubmed publisher
. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking ?-glucans. PLoS ONE. 2015;10:e0119244 pubmed publisher
Green R, Stone E, Tenno M, Lehtonen E, Farquhar M, Marth J. Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis. Immunity. 2007;27:308-20 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2535-MM/CF

SKU :

2535-MM-050/CF

product name :

Recombinant Mouse MMR/CD206 Protein, CF

Description :

The Recombinant Mouse MMR/CD206 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse MMR/CD206 Protein, CF has been validated for the following applications: Binding Activity.

target :

MMR/CD206

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

180 kDa, reducing conditions

theoretical molecular weight :

156 kDa (monomer)

gene symbol :

Mrc1

details of functionality :

Measured by its binding ability in a functional ELISA. When Mannan is coated at 0.2 µg/mL (100 µL/well), the concentration of Recombinant Mouse MMR/CD206 that produces 50% of the optimal binding response is approximately 0.1-0.6 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q2HZ94

applications :

Binding Activity

source :

NS0-derived Recombinant Mouse MMR/CD206 Protein

USD :

525 USD

alt names :

CD206, CLEC13D, CLEC13Dmacrophage mannose receptor 1, C-type lectin domain family 13 member D, mannose receptor, C type 1, MMRCD206 antigen, MRC1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage