product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MMR/CD206 Protein
catalog :
2534-MR-050
quantity :
50 ug
price :
567 USD
more info or order :
R&D Systems product webpage
citations: 11
Reference
Bruno M, Kersten S, Bain J, Jaeger M, Rosati D, Kruppa M, et al. Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris. Nat Microbiol. 2020;5:1516-1531 pubmed publisher
Duffney P, Kim H, Porter N, Jaspers I. Ozone-derived oxysterols impair lung macrophage phagocytosis via adduction of some phagocytosis receptors. J Biol Chem. 2020;295:12727-12738 pubmed publisher
Kucinskaite Kodze I, Simanavičius M, Dapkunas J, Pleckaityte M, Zvirbliene A. Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity. Biomolecules. 2020;10: pubmed publisher
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Bartheldyová E, Turánek Knötigová P, Zachova K, Masek J, Kulich P, Effenberg R, et al. N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells. Carbohydr Polym. 2019;207:521-532 pubmed publisher
Subramanian K, Neill D, Malak H, Spelmink L, Khandaker S, Dalla Libera Marchiori G, et al. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival. Nat Microbiol. 2019;4:62-70 pubmed publisher
Yang R, Wu M, Lin S, Nargund R, Li X, Kelly T, et al. A glucose-responsive insulin therapy protects animals against hypoglycemia. JCI Insight. 2018;3: pubmed publisher
Chung E, Lee G, Lee C, Ye M, Chung H, Kim H, et al. Bee Venom Phospholipase A2, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson's Disease. J Immunol. 2015;195:4853-60 pubmed publisher
. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking ?-glucans. PLoS ONE. 2015;10:e0119244 pubmed publisher
Nandakumar S, Kannanganat S, Dobos K, Lucas M, Spencer J, Fang S, et al. O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection. PLoS Pathog. 2013;9:e1003705 pubmed publisher
Gustafsson A, Sjöblom M, Strindelius L, Johansson T, Fleckenstein T, Chatzissavidou N, et al. Pichia pastoris-produced mucin-type fusion proteins with multivalent O-glycan substitution as targeting molecules for mannose-specific receptors of the immune system. Glycobiology. 2011;21:1071-86 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
2534-MR
SKU :
2534-MR-050
product name :
Recombinant Human MMR/CD206 Protein
description :
The Recombinant Human MMR/CD206 Protein from R&D Systems is derived from NS0. The Recombinant Human MMR/CD206 Protein has been validated for the following applications: Binding Activity.
target :
MMR/CD206
unit size :
50 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
160 kDa, under reducing conditions.
theoretical molecular weight :
157 kDa
gene symbol :
MRC1
details of functionality :
Measured by its binding ability in a functional ELISA. When Mannan is coated at 0.2 µg/mL (100 µL/well), the concentration of Recombinant Human MMR/CD206 that produces 50% of the optimal binding response is approximately 0.200-1.20 µg/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P22897
applications :
Binding Activity
product keywords :
2534-MR, rhMMR, hMMR,, 2534MR, CLEC 13D, Macrophage Mannose Receptor
source :
NS0-derived Recombinant Human MMR/CD206 Protein
USD :
550
USD 2025 :
567 USD
alt names :
CD206, CLEC13D, CLEC13Dmacrophage mannose receptor 1, C-type lectin domain family 13 member D, mannose receptor, C type 1, MMRCD206 antigen, MRC1
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.