Recombinant Human Integrin alpha V beta 5 Protein, CF | R&D Systems 2528-AV-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha V beta 5 Protein, CF

catalog :

2528-AV-050

quantity :

50 ug

price :

460 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Bieri M, Hendrickx R, Bauer M, Yu B, Jetzer T, Dreier B, et al. The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection. PLoS Pathog. 2021;17:e1010083 pubmed publisher
Shin S, Kim J, Park S, Jun S, Kweon H, Choi D, et al. Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth. Sci Adv. 2020;6:eaay2174 pubmed publisher
Bhatnagar S, Khera E, Liao J, Eniola V, Hu Y, Smith D, et al. Oral and Subcutaneous Administration of a Near-Infrared Fluorescent Molecular Imaging Agent Detects Inflammation in a Mouse Model of Rheumatoid Arthritis. Sci Rep. 2019;9:4661 pubmed publisher
Koh K, Cao Y, Mangos S, Tardi N, Dande R, Lee H, et al. Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist. J Clin Invest. 2019;129:1713-1726 pubmed publisher
Bönig T, Olbermann P, Bats S, Fischer W, Josenhans C. Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains. Sci Rep. 2016;6:38101 pubmed publisher
Kwon I, Hong S, Kim Y, Nam H, Kang S, Yang S, et al. Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. PLoS ONE. 2013;8:e81165 pubmed publisher

product information

brand :

R&D Systems

master code :

2528-AV

SKU :

2528-AV-050

product name :

Recombinant Human Integrin alpha V beta 5 Protein, CF

description :

The Recombinant Human Integrin alpha V beta 5 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha V beta 5 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha V beta 5

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

100-155 kDa, reducing conditions

theoretical molecular weight :

115.4 kDa ( alpha V subunit) 84.8 kDa ( beta 5 subunit)

gene symbol :

ITGAV

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Vitronectin (Catalog # 2308-VN ) is coated at 1 µg/mL, Recombinant Human Integrin alpha V beta 5 binds with an apparent KD 0.5 nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P06756 (Integrin alpha V) P18084 (Integrin beta 5)

applications :

Bioactivity

source :

CHO-derived Recombinant Human Integrin alpha V beta 5 Protein, CF

USD :

453

USD 2023 :

460 USD

alt names :

CD51, integrin subunit alpha V, ITGAV, MSK8, VNRA, VTNR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage