This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Pleiotrophin/PTN Protein, CF
catalog :
252-PL
quantity :
50 ug (also 250 ug)
price :
299 USD
citations: 4
Reference
Wong J, Krueger K, Costa M, Aggarwal A, Du H, McLaughlin T, et al. A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo. Sci Signal. 2016;9:ra103 pubmed
Nandi S, Cioce M, Yeung Y, Nieves E, Tesfa L, Lin H, et al. Receptor-type protein-tyrosine phosphatase ? is a functional receptor for interleukin-34. J Biol Chem. 2013;288:21972-86 pubmed publisher
Chen H, Campbell R, Chang Y, Li M, Wang C, Li J, et al. Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. Blood. 2009;113:1992-2002 pubmed publisher
Chen H, Gordon M, Campbell R, Li M, Wang C, Lee H, et al. Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth. Blood. 2007;110:287-95 pubmed
product information
brand :
R&D Systems
master code :
252-PL
SKU :
252-PL-050
product name :
Recombinant Human Pleiotrophin/PTN Protein, CF
description :
The Recombinant Human Pleiotrophin/PTN Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Pleiotrophin/PTN Protein, CF has been validated for the following applications: Bioactivity.
target :
Pleiotrophin/PTN
category :
Proteins and Enzymes
unit size :
50 ug (also 250 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
18 kDa, reducing conditions
theoretical molecular weight :
15.3 kDa
gene symbol :
PTN
details of functionality :
Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cerebral cortical neurons. Muramatsu, H. and T. Muramatsu (1991) Biochem. Biophys. Res. Commu. 177 :652. Optimal neurite outgrowth was observed when neurons were plated on 96 well culture plates that had been pre-coated with 100 µL/well of a solution of 3-8 µg/mL rhPTN.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
252-PL
accessionNumbers :
Q6ICQ5
applications :
Bioactivity
source :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived human Pleiotrophin/PTN protein Gly33-Asp168
2020 USD :
299
2021 USD :
299 USD
alt names :
HARP, HBBM, HB-GAM, HBGF8, HBNF, HBNF1, HBNF-1, Heparin-binding brain mitogen, HNGF-8, NEGF1HBGF-8, neurite growth-promoting factor 1, neurite growth-promoting factor1), OSF-1, Osteoblast-specific factor 1, pleiotrophin, PTN
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.