Recombinant Human Pleiotrophin/PTN Protein, CF | R&D Systems 252-PL-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Pleiotrophin/PTN Protein, CF

catalog :

252-PL-050

quantity :

50 ug (also 250 ug)

price :

373 USD

citations: 10

Reference
Sun Z, Chen Z, Yin M, Wu X, Guo B, Cheng X, et al. Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids. Cell Stem Cell. 2024;31:772-787.e11 pubmed publisher
Qin Y, Xu Y, Yi H, Shi L, Wang X, Wang W, et al. Unique structural characteristics and biological activities of heparan sulfate isolated from the mantle of the scallop Chlamys farreri. Carbohydr Polym. 2024;324:121431 pubmed publisher
Levites Y, Dammer E, Ran Y, Tsering W, Duong D, Abreha M, et al. Aβ Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease. bioRxiv. 2023;: pubmed publisher
Rajachandran S, Zhang X, Cao Q, Caldeira Brant A, Zhang X, Song Y, et al. Dissecting the spermatogonial stem cell niche using spatial transcriptomics. Cell Rep. 2023;42:112737 pubmed publisher
Lozano D, Leiva B, G xf3 mez Escalonilla I, Portal N xfa xf1 ez S, de G xf3 rtazar A, Manzano M, et al. Pleiotrophin-Loaded Mesoporous Silica Nanoparticles as a Possible Treatment for Osteoporosis. Pharmaceutics. 2023;15: pubmed publisher
Liu S, Shen M, Hsu E, Zhang C, García Marqués F, Nolley R, et al. Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer. Br J Cancer. 2021;124:896-900 pubmed publisher
Wong J, Krueger K, Costa M, Aggarwal A, Du H, McLaughlin T, et al. A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo. Sci Signal. 2016;9:ra103 pubmed
Nandi S, Cioce M, Yeung Y, Nieves E, Tesfa L, Lin H, et al. Receptor-type protein-tyrosine phosphatase ? is a functional receptor for interleukin-34. J Biol Chem. 2013;288:21972-86 pubmed publisher
Chen H, Campbell R, Chang Y, Li M, Wang C, Li J, et al. Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis. Blood. 2009;113:1992-2002 pubmed publisher
Chen H, Gordon M, Campbell R, Li M, Wang C, Lee H, et al. Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth. Blood. 2007;110:287-95 pubmed

product information

master code :

252-PL

SKU :

252-PL-050

product name :

Recombinant Human Pleiotrophin/PTN Protein, CF

unit size :

50 ug (also 250 ug)

description :

The Recombinant Human Pleiotrophin/PTN Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Pleiotrophin/PTN Protein, CF has been validated for the following applications: Bioactivity.

target :

Pleiotrophin/PTN

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

18 kDa, reducing conditions

theoretical molecular weight :

15.3 kDa

gene symbol :

PTN

details of functionality :

Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cerebral cortical neurons. Muramatsu, H. and T. Muramatsu (1991) Biochem. Biophys. Res. Commu. 177 :652. Optimal neurite outgrowth was observed when neurons were plated on 96áwell culture plates that had been pre-coated with 100 ╡L/well of a solution of 3-8á╡g/mL rhPTN.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q6ICQ5

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human Pleiotrophin/PTN protein Gly33-Asp168

source short :

Sf 21 (baculovirus)

USD :

373 USD

alt names :

HARP, HBBM, HB-GAM, HBGF8, HBNF, HBNF1, HBNF-1, Heparin-binding brain mitogen, HNGF-8, NEGF1HBGF-8, neurite growth-promoting factor 1, neurite growth-promoting factor1), OSF-1, Osteoblast-specific factor 1, pleiotrophin, PTN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.