Recombinant Human LIFR alpha Protein, CF | R&D Systems 249-LR-050/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human LIFR alpha Protein, CF

catalog :

249-LR-050/CF

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Chollangi S, Mather T, Rodgers K, Ash J. A unique loop structure in oncostatin M determines binding affinity toward oncostatin M receptor and leukemia inhibitory factor receptor. J Biol Chem. 2012;287:32848-59 pubmed
Abir R, Fisch B, Jin S, Barnnet M, Freimann S, van den Hurk R, et al. Immunocytochemical detection and RT-PCR expression of leukaemia inhibitory factor and its receptor in human fetal and adult ovaries. Mol Hum Reprod. 2004;10:313-9 pubmed
Erices A, Conget P, Rojas C, Minguell J. Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells. Exp Cell Res. 2002;280:24-32 pubmed

product information

master code :

249-LR/CF

SKU :

249-LR-050/CF

product name :

Recombinant Human LIFR alpha Protein, CF

unit size :

50 ug

description :

The Recombinant Human LIFR alpha Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human LIFR alpha Protein, CF has been validated for the following applications: Bioactivity.

target :

LIFR alpha

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

100-110 kDa, reducing conditions

theoretical molecular weight :

89 kDa

gene symbol :

LIFR

details of functionality :

Measured by its ability to inhibit LIF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 3-10 ╡g/mL in the presence of 0.3 ng/mL of recombinant human LIF.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P42702

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human LIF R alpha protein Gln45-Ser833

source short :

Sf 21 (baculovirus)

USD :

432 USD

alt names :

CD118, CD118 antigen, FLJ98106, FLJ99923, leukemia inhibitory factor receptor, leukemia inhibitory factor receptor alpha, LIF R alpha, LIF R beta, LIF receptor, LIFR, LIF-R, LIFRa, SJS2, STWS, SWS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage