Human Serpin G1/C1 Inhibitor (Plasma) Protein, CF | R&D Systems 2488-PI-200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Human Serpin G1/C1 Inhibitor (Plasma) Protein, CF

catalog :

2488-PI-200

quantity :

200 ug

price :

322 USD

citations: 4

Reference
Kraaijvanger R, Janssen Bon xe1 s M, Grutters J, Paspali I, Veltkamp M, de Kleijn D, et al. Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis. Respir Res. 2024;25:166 pubmed publisher
Amann T, Hansen A, Kol S, Hansen H, Arnsdorf J, Nallapareddy S, et al. Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles. Metab Eng. 2019;52:143-152 pubmed publisher
Zhang Y, Vernooij F, Ibrahim I, Ooi S, Gijsberts C, Schoneveld A, et al. Extracellular Vesicle Proteins Associated with Systemic Vascular Events Correlate with Heart Failure: An Observational Study in a Dyspnoea Cohort. PLoS ONE. 2016;11:e0148073 pubmed publisher
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed

product information

master code :

2488-PI

SKU :

2488-PI-200

product name :

Human Serpin G1/C1 Inhibitor (Plasma) Protein, CF

unit size :

200 ug

description :

The Human Serpin G1/C1 Inhibitor (Plasma) Protein, CF from R&D Systems is derived from Human Plasma. The Human Serpin G1/C1 Inhibitor (Plasma) Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Serpin G1/C1 Inhibitor

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Sodium Acetate and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

93 kDa, reducing conditions

gene symbol :

SERPING1

details of functionality :

Measured by its ability to inhibit Recombinant Human Complement Component C1s (Catalog # 2060-SE ) cleavage of a colorimetric peptide substrate, N-carbobenzyloxy-Lys-ThioBenzyl ester (Z-K-SBzl). The IC50 is 2.6 nM, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

applications :

Inhibition Activity

source long :

Human plasma-derived Serpin G1/C1 Inhibitor protein The human plasma used for the isolation of this product were certified by the supplier to be HIV-1 and HBsAg negative at the time of shipment. Human blood products should always be treated in accordance with universal handling precautions.

source short :

Human Plasma

USD :

322 USD

alt names :

C1 Inhibitor, C1IN, C1INH, C1NH, HAE1, HAE2, SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.