product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human BDNF Protein, CF
catalog :
248-BDB-050/CF
quantity :
50 ug (also 10 ug, 250 ug, 1 mg)
price :
755 USD
more info or order :
citations: 203
Reference
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Patnaik A, Spiombi E, Frasca A, Landsberger N, Zagrebelsky M, Korte M. Fingolimod Modulates Dendritic Architecture in a BDNF-Dependent Manner. Int J Mol Sci. 2020;21: pubmed publisher
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Ozair M, Kirst C, van den Berg B, Ruzo A, Rito T, Brivanlou A. hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate. Cell Stem Cell. 2018;23:60-73.e6 pubmed publisher
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image
image 1 :
R&D Systems 248-BDB-050/CF image 1
Recombinant Human BDNF Protein Bioactivity
product information
brand :
R&D Systems
master code :
248-BDB/CF
SKU :
248-BDB-050/CF
product name :
Recombinant Human BDNF Protein, CF
description :
The Recombinant Human BDNF Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human BDNF Protein, CF has been validated for the following applications: Bioactivity.
target :
BDNF
category :
Proteins and Enzymes
sizes available :
50 ug (also 10 ug, 250 ug, 1 mg)
buffer :
Lyophilized from a 0.2 µm filtered solution in Sodium Citrate and NaCl.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human, Mouse, Rat, Canine, Equine
observed molecular weight :
13-14 kDa, under reducing conditions.
theoretical molecular weight :
13.5 kDa
details of functionality :
Measured in a cell proliferation assay using BaF mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.2-2 ng/mL Measured by its binding ability in a functional ELISA. When Recombinant Human TrkB Fc Chimera (Catalog # 688-TK ) is coated at 1 µg/mL, Recombinant Human BDNF binds with an apparent Kd 1 nM.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P23560
applications :
Bioactivity
extended description :
100% sequence homology with Mouse, Rat, Canine, Equine and all other mammalian proteins examined. Earn double rewards for reviews
source :
Sf 21 (baculovirus)-derived Recombinant Human BDNF Protein, CF
USD :
755
USD 2023 :
755 USD
product details :
100% sequence homology with Mouse, Rat, Canine, Equine and all other mammalian proteins examined. Earn double rewards for reviews
alt names :
abrineurin, ANON2, brain-derived neurotrophic factor, BULN2, MGC34632, neurotrophin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.