Recombinant Human TfR Protein, CF | R&D Systems 2474-TR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TfR Protein, CF

catalog :

2474-TR-050

quantity :

50 ug

price :

428 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Cohen C, Coulon S, Bhukhai K, Neuraz A, Dussiot M, Fouquet G, et al. Erythrocytosis associated with IgA nephropathy. EBioMedicine. 2022;75:103785 pubmed publisher
Guan J, Liu X, Zhang H, Lv Y, Wang X, Yang X, et al. Generation of an iPSC line (SDQLCHi015-A) from peripheral blood mononuclear cells of a patient with mental retardation type 15 carrying c.1007_1011del, p.(Ile336fs) in CUL4B gene. Stem Cell Res. 2019;41:101628 pubmed publisher
García Valdés L, Campoy C, Hayes H, Florido J, Rusanova I, Miranda M, et al. The impact of maternal obesity on iron status, placental transferrin receptor expression and hepcidin expression in human pregnancy. Int J Obes (Lond). 2015;39:571-8 pubmed publisher
Sade H, Baumgartner C, Hugenmatter A, Moessner E, Freskgård P, Niewoehner J. A human blood-brain barrier transcytosis assay reveals antibody transcytosis influenced by pH-dependent receptor binding. PLoS ONE. 2014;9:e96340 pubmed publisher

image

image 1 :

Graph showing dose-dependent bioactivity of Human TfR protein

product information

brand :

R&D Systems

master code :

2474-TR

SKU :

2474-TR-050

product name :

Recombinant Human TfR Protein, CF

description :

The Recombinant Human TfR Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TfR Protein, CF has been validated for the following applications: Bioactivity.

target :

TfR (Transferrin R)

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris and NaCl with Trehalose.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

76-85 kDa, reducing conditions

theoretical molecular weight :

76 kDa

gene symbol :

TFRC

details of functionality :

Measured by its binding ability in a functional ELISA. When human Holo-Transferrin (Catalog # 2914-HT) is coated at 0.5 µg/mL (100 µL/well), the concentration of rhTfR that produces 50% of the optimal binding response is found to be approximately 3-12 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

CAA25527

applications :

Bioactivity

source :

NS0-derived Recombinant Human TfR Protein, CF

USD :

421

USD 2023 :

428 USD

alt names :

CD71, CD71 antigen, CD71TRFR, p90, T9, TfR, TfR (TransferrinR), TFR1, TFRC, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage