| Reference |
|---|
Michaels Y, Edgar J, Major M, Castle E, Zimmerman C, Yin T, et al. DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells. Sci Adv. 2022;8:eabn5522 pubmed publisher |
Hagemann K, Riecken K, Jung J, Hildebrandt H, Menzel S, Bunders M, et al. Natural killer cell-mediated ADCC in SARS-CoV-2-infected individuals and vaccine recipients. Eur J Immunol. 2022;52:1297-1307 pubmed publisher |
Chu T, Vo M, Lakshmi T, Ahn S, Kim M, Song G, et al. Novel IL-15 dendritic cells have a potent immunomodulatory effect in immunotherapy of multiple myeloma. Transl Oncol. 2022;20:101413 pubmed publisher |
Sekhri P, Ledezma D, Shukla A, Sweeney E, Fernandes R. The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells. Cancers (Basel). 2022;14: pubmed publisher |
Liang H, Costanza M, Prutsch N, Zimmerman M, Gurnhofer E, Montes Mojarro I, et al. Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma. Nat Commun. 2021;12:5577 pubmed publisher |
Pino M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, Khan A, Ryan E, et al. Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART. PLoS Pathog. 2021;17:e1009825 pubmed publisher |
David G, Willem C, Legrand N, Djaoud Z, M xe9 rieau P, Walencik A, et al. Deciphering the biology of KIR2DL3+ T lymphocytes that are associated to relapse in haploidentical HSCT. Sci Rep. 2021;11:15782 pubmed publisher |
Bear A, Blanchard T, Cesare J, Ford M, Richman L, Xu C, et al. Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting. Nat Commun. 2021;12:4365 pubmed publisher |
Basar R, Uprety N, Ensley E, Daher M, Klein K, Martinez F, et al. Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy. Cell Rep. 2021;36:109432 pubmed publisher |
Pieren D, Smits N, Hoeboer J, Kandiah V, Postel R, Mariman R, et al. Regulatory KIR+ RA+ T cells accumulate with age and are highly activated during viral respiratory disease. Aging Cell. 2021;20:e13372 pubmed publisher |
Rossignol E, Dugast A, Compere H, Cottrell C, Copps J, Lin S, et al. Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells. Cell Rep. 2021;35:109167 pubmed publisher |
Hasan F, Chiu Y, Shaw R, Wang J, Yee C. Hypoxia acts as an environmental cue for the human tissue-resident memory T cell differentiation program. JCI Insight. 2021;6: pubmed publisher |
Emmons T, Giridharan T, Singel K, Khan A, Ricciuti J, Howard K, et al. Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer. Cancer Immunol Res. 2021;9:790-810 pubmed publisher |
Bakker O, Ram xed rez S xe1 nchez A, Borek Z, de Klein N, Li Y, Modderman R, et al. Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells. Sci Rep. 2021;11:9252 pubmed publisher |
Farhat A, Weiner A, Posner C, Kim Z, Orcutt Jahns B, Carlson S, et al. Modeling cell-specific dynamics and regulation of the common gamma chain cytokines. Cell Rep. 2021;35:109044 pubmed publisher |
Jung S, Appleton E, Ali M, Church G, del Sol A. A computer-guided design tool to increase the efficiency of cellular conversions. Nat Commun. 2021;12:1659 pubmed publisher |
Singh A, Schetzen E, Yadav S, Lustig E, Liu W, Yadav R, et al. Correction of murine sickle cell disease by allogeneic haematopoietic cell transplantation with anti-3rd party veto cells. Bone Marrow Transplant. 2021;56:1818-1827 pubmed publisher |
Gimenez N, Tripathi R, Giró A, Rosich L, Lopez Guerra M, López Oreja I, et al. Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia. Sci Rep. 2020;10:22153 pubmed publisher |
Naidoo K, Shangase Z, Rashid T, Ngubane A, Ismail N, Ndung u T, et al. The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans. PLoS ONE. 2020;15:e0242448 pubmed publisher |
Mbiribindi B, Pena J, Arvedson M, Moreno Romero C, McCarthy S, Hatton O, et al. Epstein-Barr virus peptides derived from latent cycle proteins alter NKG2A + NK cell effector function. Sci Rep. 2020;10:19973 pubmed publisher |
Panigrahi S, Chen B, Fang M, Potashnikova D, Komissarov A, Lebedeva A, et al. CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis. PLoS Pathog. 2020;16:e1008885 pubmed publisher |
Aram J, Frakich N, Morandi E, Alrouji M, Samaraweera A, Onion D, et al. Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis. Biomedicines. 2020;8: pubmed publisher |
Schober S, Thiede M, Gassmann H, Prexler C, Xue B, Schirmer D, et al. MHC Class I-Restricted TCR-Transgenic CD4+ T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo. Cells. 2020;9: pubmed publisher |
Gerstenberger B, Banker M, Clark J, Dowty M, Fensome A, Gifford R, et al. Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences. Sci Rep. 2020;10:8974 pubmed publisher |
Morris S, Chen B, Mudd J, Panigrahi S, Shive C, Sieg S, et al. Inflammescent CX3CR1+CD57+CD8+ T cells are generated and expanded by IL-15. JCI Insight. 2020;5: pubmed publisher |
Fonseca R, Beura L, Quarnstrom C, Ghoneim H, Fan Y, Zebley C, et al. Developmental plasticity allows outside-in immune responses by resident memory T cells. Nat Immunol. 2020;21:412-421 pubmed publisher |
McBrien J, Mavigner M, Franchitti L, Smith S, White E, Tharp G, et al. Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells. Nature. 2020;578:154-159 pubmed publisher |
Swadling L, Pallett L, Diniz M, Baker J, Amin O, Stegmann K, et al. Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence. Cell Rep. 2020;30:687-698.e6 pubmed publisher |
Nguyen D, Roth T, Li P, Chen P, Apathy R, Mamedov M, et al. Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency. Nat Biotechnol. 2020;38:44-49 pubmed publisher |
Quintarelli C, Sivori S, Caruso S, Carlomagno S, Falco M, Boffa I, et al. Efficacy of third-party chimeric antigen receptor modified peripheral blood natural killer cells for adoptive cell therapy of B-cell precursor acute lymphoblastic leukemia. Leukemia. 2020;34:1102-1115 pubmed publisher |
Lopez Guerra M, Xargay Torrent S, Fuentes P, Roldán J, González Farre B, Rosich L, et al. Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells. Oncogene. 2020;39:1185-1197 pubmed publisher |
Ventura J, Beloor J, Allen E, Zhang T, Haugh K, Uchil P, et al. Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice. PLoS Pathog. 2019;15:e1008161 pubmed publisher |
Li Z, Zhou J, Luo C, Zhang L. Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II‑induced arthritis. Mol Med Rep. 2019;20:4540-4550 pubmed publisher |
Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed publisher |
Wonderlich E, Subramanian K, Cox B, Wiegand A, Lackman Smith C, Bale M, et al. Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals. PLoS Pathog. 2019;15:e1008074 pubmed publisher |
Renner K, Bruss C, Schnell A, Koehl G, Becker H, Fante M, et al. Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. Cell Rep. 2019;29:135-150.e9 pubmed publisher |
Gras Navarro A, Espedal H, Joseph J, Trachsel Moncho L, Bahador M, Gjertsen B, et al. Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival. Cancers (Basel). 2019;11: pubmed publisher |
Lam V, Folkersen L, Aguilar O, Lanier L. KLF12 Regulates Mouse NK Cell Proliferation. J Immunol. 2019;203:981-989 pubmed publisher |
Kim E, De Leon A, Jiang Z, Radu R, Martineau A, Chan E, et al. Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis. mSphere. 2019;4: pubmed publisher |
Yoo H, Liu Y, Wang L, Schubert M, Hoffmann J, Wang S, et al. Tumor-Specific Reactive Oxygen Species Accelerators Improve Chimeric Antigen Receptor T Cell Therapy in B Cell Malignancies. Int J Mol Sci. 2019;20: pubmed publisher |
Yang W, Lee K, Srivastava R, Kuo F, Krishna C, Chowell D, et al. Immunogenic neoantigens derived from gene fusions stimulate T cell responses. Nat Med. 2019;25:767-775 pubmed publisher |
Kuranda K, Caillat Zucman S, You S, Mallone R. In Vitro Expansion of Anti-viral T Cells from Cord Blood by Accelerated Co-cultured Dendritic Cells. Mol Ther Methods Clin Dev. 2019;13:112-120 pubmed publisher |
Solà Riera C, Gupta S, Ljunggren H, Klingstrom J. Orthohantaviruses belonging to three phylogroups all inhibit apoptosis in infected target cells. Sci Rep. 2019;9:834 pubmed publisher |
Schleiss C, Ilias W, Tahar O, Güler Y, Miguet L, Mayeur Rousse C, et al. BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo. Sci Rep. 2019;9:701 pubmed publisher |
Kim S, Lewis J, Cyrenne B, Monico P, Mirza F, Carlson K, et al. BET inhibition in advanced cutaneous T cell lymphoma is synergistically potentiated by BCL2 inhibition or HDAC inhibition. Oncotarget. 2018;9:29193-29207 pubmed publisher |
Zhao X, Sankaran S, Yap J, Too C, Ho Z, Dolton G, et al. Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Nat Commun. 2018;9:2716 pubmed publisher |
Kim E, Teles R, Haile S, Liu P, Modlin R. Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae. PLoS Negl Trop Dis. 2018;12:e0006608 pubmed publisher |
Correia M, Stojanovic A, Bauer K, Juraeva D, Tykocinski L, Lorenz H, et al. Distinct human circulating NKp30+FcεRIγ+CD8+ T cell population exhibiting high natural killer-like antitumor potential. Proc Natl Acad Sci U S A. 2018;115:E5980-E5989 pubmed publisher |
Rodríguez Alvarez Y, Cabrales Rico A, Perera Pintado A, Prats Capote A, Garay Pérez H, Reyes Acosta O, et al. In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays. J Pept Sci. 2018;24:e3078 pubmed publisher |
Golden Mason L, McMahan R, Kriss M, Kilgore A, Cheng L, Dran R, et al. Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment. Hepatol Commun. 2018;2:364-375 pubmed publisher |
Liu R, Merola J, Manes T, Qin L, Tietjen G, Lopez Giraldez F, et al. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight. 2018;3: pubmed publisher |
Oth T, Habets T, Germeraad W, Zonneveld M, Bos G, Vanderlocht J. Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-γ. BMC Immunol. 2018;19:8 pubmed publisher |
Thepmalee C, Panya A, Junking M, Chieochansin T, Yenchitsomanus P. Inhibition of IL-10 and TGF-β receptors on dendritic cells enhances activation of effector T-cells to kill cholangiocarcinoma cells. Hum Vaccin Immunother. 2018;14:1423-1431 pubmed publisher |
Felices M, Lenvik A, McElmurry R, Chu S, Hinderlie P, Bendzick L, et al. Continuous treatment with IL-15 exhausts human NK cells via a metabolic defect. JCI Insight. 2018;3: pubmed publisher |
Turaj A, Cox K, Penfold C, French R, Mockridge C, Willoughby J, et al. Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking. Sci Rep. 2018;8:2278 pubmed publisher |
Najar M, Fayyad Kazan M, Meuleman N, Bron D, Fayyad Kazan H, Lagneaux L. Mesenchymal stromal cells of the bone marrow and natural killer cells: cell interactions and cross modulation. J Cell Commun Signal. 2018;12:673-688 pubmed publisher |
Ende Z, Deymier M, Claiborne D, Prince J, Mónaco D, Kilembe W, et al. HLA Class I Downregulation by HIV-1 Variants from Subtype C Transmission Pairs. J Virol. 2018;92: pubmed publisher |
Gavegnano C, Brehm J, Dupuy F, Talla A, Ribeiro S, Kulpa D, et al. Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors. PLoS Pathog. 2017;13:e1006740 pubmed publisher |
Kuca Warnawin E, Kurowska W, Prochorec Sobieszek M, Radzikowska A, Burakowski T, Skalska U, et al. Rheumatoid arthritis bone marrow environment supports Th17 response. Arthritis Res Ther. 2017;19:274 pubmed publisher |
Lin J, Du N, Li P, Kazemian M, Gebregiorgis T, Spolski R, et al. Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells. Nat Commun. 2017;8:1320 pubmed publisher |
Clénet M, Gagnon F, Moratalla A, Viel E, Arbour N. Peripheral human CD4+CD8+ T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15. Sci Rep. 2017;7:11612 pubmed publisher |
Li W, Wu Y, Kong D, Yang H, Wang Y, Shao J, et al. One-domain CD4 Fused to Human Anti-CD16 Antibody Domain Mediates Effective Killing of HIV-1-Infected Cells. Sci Rep. 2017;7:9130 pubmed publisher |
Ramos C, Ballard B, Zhang H, Dakhova O, Gee A, Mei Z, et al. Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes. J Clin Invest. 2017;127:3462-3471 pubmed publisher |
Wu S, Chang C, Hsu J, Lu M, Lai N, Li C, et al. Hydroxychloroquine inhibits CD154 expression in CD4+ T lymphocytes of systemic lupus erythematosus through NFAT, but not STAT5, signaling. Arthritis Res Ther. 2017;19:183 pubmed publisher |
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher |
Heczey A, Louis C, Savoldo B, Dakhova O, Durett A, Grilley B, et al. CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma. Mol Ther. 2017;25:2214-2224 pubmed publisher |
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, et al. Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities. Oncoimmunology. 2017;6:e1283460 pubmed publisher |
Zhang Z, He Q, Tao Y, Guo J, Xu F, Wu L, et al. Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes. Am J Transl Res. 2017;9:454-465 pubmed |
Felices M, Chu S, Kodal B, Bendzick L, Ryan C, Lenvik A, et al. IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer. Gynecol Oncol. 2017;145:453-461 pubmed publisher |
Tanaka M, Tashiro H, Omer B, Lapteva N, Ando J, Ngo M, et al. Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells. Clin Cancer Res. 2017;23:3499-3509 pubmed publisher |
Kerstein A, Schüler S, Cabral Marques O, Fazio J, Häsler R, Muller A, et al. Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis. J Autoimmun. 2017;78:79-91 pubmed publisher |
Goto K, Annan D, Morita T, Li W, Muroyama R, Matsubara Y, et al. Novel chemoimmunotherapeutic strategy for hepatocellular carcinoma based on a genome-wide association study. Sci Rep. 2016;6:38407 pubmed publisher |
Wege A, Weber F, Kroemer A, Ortmann O, Nimmerjahn F, Brockhoff G. IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM). Oncotarget. 2017;8:2731-2744 pubmed publisher |
Yeap W, Wong K, Shimasaki N, Teo E, Quek J, Yong H, et al. CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes. Sci Rep. 2016;6:34310 pubmed publisher |
Gill U, Peppa D, Micco L, Singh H, Carey I, Foster G, et al. Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo. PLoS Pathog. 2016;12:e1005788 pubmed publisher |
Murata K, Tsukahara T, Emori M, Shibayama Y, Mizushima E, Matsumiya H, et al. Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance. Oncoimmunology. 2016;5:e1165376 pubmed publisher |
Yamada D, Iyoda T, Vizcardo R, Shimizu K, Sato Y, Endo T, et al. Efficient Regeneration of Human Vα24+ Invariant Natural Killer T Cells and Their Anti-Tumor Activity In Vivo. Stem Cells. 2016;34:2852-2860 pubmed publisher |
Bonifant C, Szöor A, Torres D, Joseph N, Velasquez M, Iwahori K, et al. CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia. Mol Ther. 2016;24:1615-26 pubmed publisher |
Younes S, Freeman M, Mudd J, Shive C, Reynaldi A, Panigrahi S, et al. IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. J Clin Invest. 2016;126:2745-56 pubmed publisher |
Pulko V, Davies J, Martinez C, Lanteri M, Busch M, Diamond M, et al. Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses. Nat Immunol. 2016;17:966-75 pubmed publisher |
Jones R, Mueller S, O Connor R, Rimpel K, Sloan D, Karel D, et al. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog. 2016;12:e1005545 pubmed publisher |
Pedroza Pacheco I, Shah D, Domogala A, Luevano M, Blundell M, Jackson N, et al. Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Sci Rep. 2016;6:22097 pubmed publisher |
Thomas S, Klobuch S, Podlech J, Plachter B, Hoffmann P, Renzaho A, et al. Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice. PLoS Pathog. 2015;11:e1005049 pubmed publisher |
Mongini P, Gupta R, Boyle E, Nieto J, Lee H, Stein J, et al. TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells. J Immunol. 2015;195:901-23 pubmed publisher |
Brückner S, Agnandji S, Berberich S, Bache E, Fernandes J, Schweiger B, et al. Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial. PLoS Negl Trop Dis. 2015;9:e0003768 pubmed publisher |
Yokota S, Yoshida O, Dou L, Spadaro A, Isse K, Ross M, et al. IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production. J Immunol. 2015;194:6045-56 pubmed publisher |
Jacomet F, Cayssials E, Basbous S, Levescot A, Piccirilli N, Desmier D, et al. Evidence for eomesodermin-expressing innate-like CD8(+) KIR/NKG2A(+) TÂ cells in human adults and cord blood samples. Eur J Immunol. 2015;45:1926-33 pubmed publisher |
Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos G, Eyerman A, Lytton Jean A, et al. Ex vivo cytosolic delivery of functional macromolecules to immune cells. PLoS ONE. 2015;10:e0118803 pubmed publisher |
Broux B, Mizee M, Vanheusden M, van der Pol S, van Horssen J, Van Wijmeersch B, et al. IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis. J Immunol. 2015;194:2099-109 pubmed publisher |
Li H, Richert Spuhler L, Evans T, Gillis J, Connole M, Estes J, et al. Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. PLoS Pathog. 2014;10:e1004551 pubmed publisher |
Arber C, Feng X, Abhyankar H, Romero E, Wu M, Heslop H, et al. Survivin-specific T cell receptor targets tumor but not T cells. J Clin Invest. 2015;125:157-68 pubmed publisher |
Nair S, Fang M, Sigal L. The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by IL-15/IL-15Rα treatment. Aging Cell. 2015;14:180-90 pubmed publisher |
Lam S, Sung J, Cruz C, Castillo Caro P, Ngo M, Garrido C, et al. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Mol Ther. 2015;23:387-95 pubmed publisher |
Hoyer S, Prommersberger S, Pfeiffer I, Schuler Thurner B, Schuler G, Dörrie J, et al. Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango. Eur J Immunol. 2014;44:3543-59 pubmed publisher |
Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk. J Immunol. 2014;193:2297-305 pubmed publisher |
Golden Mason L, Hahn Y, Strong M, Cheng L, Rosen H. Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection. PLoS ONE. 2014;9:e103219 pubmed publisher |
Cupi M, Sarra M, De Nitto D, Franzè E, Marafini I, Monteleone I, et al. Defective expression of scavenger receptors in celiac disease mucosa. PLoS ONE. 2014;9:e100980 pubmed publisher |
Volpe E, Pattarini L, Martinez Cingolani C, Meller S, Donnadieu M, Bogiatzi S, et al. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis. J Allergy Clin Immunol. 2014;134:373-81 pubmed publisher |
Geyeregger R, Freimüller C, Stemberger J, Fischer G, Witt V, Fritsch G. Human AdV-specific T cells: persisting in vitro functionality despite lethal irradiation. Bone Marrow Transplant. 2014;49:934-41 pubmed publisher |
Mao C, Mou X, Zhou Y, Yuan G, Xu C, Liu H, et al. Tumor-activated TCR??? T cells from gastric cancer patients induce the antitumor immune response of TCR??? T cells via their antigen-presenting cell-like effects. J Immunol Res. 2014;2014:593562 pubmed publisher |
Leen A, Sukumaran S, Watanabe N, Mohammed S, Keirnan J, Yanagisawa R, et al. Reversal of tumor immune inhibition using a chimeric cytokine receptor. Mol Ther. 2014;22:1211-1220 pubmed publisher |
Harris K, Ramachandran G, Basu S, Rollins S, Mann D, Cross A. The IL-23/Th17 axis is involved in the adaptive immune response to Bacillus anthracis in humans. Eur J Immunol. 2014;44:752-62 pubmed publisher |
Banu N, Chia A, Ho Z, Garcia A, Paravasivam K, Grotenbreg G, et al. Building and optimizing a virus-specific T cell receptor library for targeted immunotherapy in viral infections. Sci Rep. 2014;4:4166 pubmed publisher |
Lowe R, Genin A, Orgun N, Cron R. IL-15 prolongs CD154 expression on human CD4 T cells via STAT5 binding to the CD154 transcriptional promoter. Genes Immun. 2014;15:137-44 pubmed publisher |
Bojarczuk K, Siernicka M, Dwojak M, Bobrowicz M, Pyrzynska B, Gaj P, et al. B-cell receptor pathway inhibitors affect CD20 levels and impair antitumor activity of anti-CD20 monoclonal antibodies. Leukemia. 2014;28:1163-7 pubmed publisher |
Bastidas S, Graw F, Smith M, Kuster H, Gunthard H, Oxenius A. CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals. J Immunol. 2014;192:1732-44 pubmed publisher |
Uttenthal B, Martínez Dávila I, Ivey A, Craddock C, Chen F, Virchis A, et al. Wilms' Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses. Br J Haematol. 2014;164:366-75 pubmed publisher |
Sommi P, Necchi V, Vitali A, Montagna D, De Luigi A, Salmona M, et al. PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors. PLoS ONE. 2013;8:e82560 pubmed publisher |
Messaoudene M, Fregni G, Fourmentraux Neves E, Chanal J, Maubec E, Mazouz Dorval S, et al. Mature cytotoxic CD56(bright)/CD16(+) natural killer cells can infiltrate lymph nodes adjacent to metastatic melanoma. Cancer Res. 2014;74:81-92 pubmed publisher |
Romero A, Chaput N, Poirier Colame V, Rusakiewicz S, Jacquelot N, Chaba K, et al. Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15R? and NKG2D triggering. Cancer Res. 2014;74:68-80 pubmed publisher |
Borrelli M, Salvati V, Maglio M, Zanzi D, Ferrara K, Santagata S, et al. Immunoregulatory pathways are active in the small intestinal mucosa of patients with potential celiac disease. Am J Gastroenterol. 2013;108:1775-84 pubmed publisher |
Carlson L, De Geer A, Sveinbjørnsson B, Orrego A, Martinsson T, Kogner P, et al. The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytes. Oncoimmunology. 2013;2:e23618 pubmed |
Geyeregger R, Freimüller C, Stevanovic S, Stemberger J, Mester G, Dmytrus J, et al. Short-term in-vitro expansion improves monitoring and allows affordable generation of virus-specific T-cells against several viruses for a broad clinical application. PLoS ONE. 2013;8:e59592 pubmed publisher |
Lin G, Snell L, Wortzman M, Clouthier D, Watts T. GITR-dependent regulation of 4-1BB expression: implications for T cell memory and anti-4-1BB-induced pathology. J Immunol. 2013;190:4627-39 pubmed publisher |
Dong J, Chang H, Ivascu C, Qian Y, Rezai S, Okhrimenko A, et al. Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-? memory in human CD4(+) T lymphocytes. Eur J Immunol. 2013;43:793-804 pubmed publisher |
Alonzo F, Kozhaya L, Rawlings S, Reyes Robles T, Dumont A, Myszka D, et al. CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. Nature. 2013;493:51-5 pubmed publisher |
Sarra M, Cupi M, Monteleone I, Franzè E, Ronchetti G, Di Sabatino A, et al. IL-15 positively regulates IL-21 production in celiac disease mucosa. Mucosal Immunol. 2013;6:244-55 pubmed publisher |
Mujib S, Jones R, Lo C, Aidarus N, Clayton K, Sakhdari A, et al. Antigen-independent induction of Tim-3 expression on human T cells by the common ?-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway. J Immunol. 2012;188:3745-56 pubmed publisher |
Dupuy S, Lambert M, Zucman D, Choukem S, Tognarelli S, Pagès C, et al. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog. 2012;8:e1002486 pubmed publisher |
Andresen L, Skovbakke S, Persson G, Hagemann Jensen M, Hansen K, Jensen H, et al. 2-deoxy D-glucose prevents cell surface expression of NKG2D ligands through inhibition of N-linked glycosylation. J Immunol. 2012;188:1847-55 pubmed publisher |
Ichii M, Frank M, Iozzo R, Kincade P. The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood. 2012;119:1683-92 pubmed publisher |
Mamessier E, Sylvain A, Thibult M, Houvenaeghel G, Jacquemier J, Castellano R, et al. Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity. J Clin Invest. 2011;121:3609-22 pubmed publisher |
Milpied P, Massot B, Renand A, Diem S, Herbelin A, Leite de Moraes M, et al. IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood. 2011;118:2993-3002 pubmed publisher |
Zhang H, Song K, Rabin R, Hill B, Perfetto S, Roederer M, et al. CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. J Immunol. 2010;185:6646-63 pubmed publisher |
Ramana Rao P, Rajasekaran S, Raja A. Natural killer cell-mediated cytokine response among HIV-positive south Indians with pulmonary tuberculosis. J Interferon Cytokine Res. 2010;30:33-42 pubmed publisher |
Kwant Mitchell A, Pek E, Rosenthal K, Ashkar A. Development of functional human NK cells in an immunodeficient mouse model with the ability to provide protection against tumor challenge. PLoS ONE. 2009;4:e8379 pubmed publisher |
Erlendsson L, Muench M, Hellman U, Hrafnkelsdóttir S, Jonsson A, Balmer Y, et al. Barley as a green factory for the production of functional Flt3 ligand. Biotechnol J. 2010;5:163-71 pubmed publisher |
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed publisher |
Giron Michel J, Menard F, Negrini S, Devocelle A, Azzarone B, Besson C. EBV-associated mononucleosis does not induce long-term global deficit in T-cell responsiveness to IL-15. Blood. 2009;113:4541-7 pubmed publisher |
Eid R, Rao D, Zhou J, Lo S, Ranjbaran H, Gallo A, et al. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation. 2009;119:1424-32 pubmed publisher |
Kitaya K, Yasuo T. Dermatan sulfate proteoglycan biglycan as a potential selectin L/CD44 ligand involved in selective recruitment of peripheral blood CD16(-) natural killer cells into human endometrium. J Leukoc Biol. 2009;85:391-400 pubmed publisher |
Vossen M, Matmati M, Hertoghs K, Baars P, Gent M, Leclercq G, et al. CD27 defines phenotypically and functionally different human NK cell subsets. J Immunol. 2008;180:3739-45 pubmed |
McCullar V, Oostendorp R, Panoskaltsis Mortari A, Yun G, Lutz C, Wagner J, et al. Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15. Exp Hematol. 2008;36:598-608 pubmed publisher |
Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J Immunol Methods. 2008;329:214-8 pubmed |
de Matos C, Berg L, Michaelsson J, Fellander Tsai L, Kärre K, Soderstrom K. Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion. Immunology. 2007;122:291-301 pubmed |
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed |
Eidenschenk C, Jouanguy E, Alcais A, Mention J, Pasquier B, Fleckenstein I, et al. Familial NK cell deficiency associated with impaired IL-2- and IL-15-dependent survival of lymphocytes. J Immunol. 2006;177:8835-43 pubmed |
Hirahara K, Liu L, Clark R, Yamanaka K, Fuhlbrigge R, Kupper T. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J Immunol. 2006;177:4488-94 pubmed |
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed |
Goff W, Storset A, Johnson W, Brown W. Bovine splenic NK cells synthesize IFN-gamma in response to IL-12-containing supernatants from Babesia bovis-exposed monocyte cultures. Parasite Immunol. 2006;28:221-8 pubmed |
Cho M, Min S, Chang S, Kim K, Heo S, Lee S, et al. Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression. Immunol Lett. 2006;105:159-66 pubmed |
Hanabuchi S, Watanabe N, Wang Y, Wang Y, Ito T, Shaw J, et al. Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL). Blood. 2006;107:3617-23 pubmed |
Von Strandmann E, Hansen H, Reiners K, Schnell R, Borchmann P, Merkert S, et al. A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo. Blood. 2006;107:1955-62 pubmed |
Alves N, Arosa F, van Lier R. IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells. J Immunol. 2005;175:755-62 pubmed |
Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, et al. Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism. J Immunol. 2005;174:2376-86 pubmed |
Tejman Yarden N, Zlotnik M, Lewis E, Etzion O, Chaimovitz C, Douvdevani A. Renal cells express a functional interleukin-15 receptor. Nephrol Dial Transplant. 2005;20:516-23 pubmed |
Conklyn M, Andresen C, Changelian P, Kudlacz E. The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing. J Leukoc Biol. 2004;76:1248-55 pubmed |
Kao C, Chen Y, Thai P, Wachi S, Huang F, Kim C, et al. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol. 2004;173:3482-91 pubmed |
Ciree A, Michel L, Camilleri Broet S, Jean Louis F, Oster M, Flageul B, et al. Expression and activity of IL-17 in cutaneous T-cell lymphomas (mycosis fungoides and Sezary syndrome). Int J Cancer. 2004;112:113-20 pubmed |
Yamasaki S, Maeda M, Ohshima K, Kikuchi M, Otsuka T, Harada M. Growth and apoptosis of human natural killer cell neoplasms: role of interleukin-2/15 signaling. Leuk Res. 2004;28:1023-31 pubmed |
Brady J, Hayakawa Y, Smyth M, Nutt S. IL-21 induces the functional maturation of murine NK cells. J Immunol. 2004;172:2048-58 pubmed |
Calarota S, Otero M, Hermanstyne K, Hermanstayne K, Lewis M, Rosati M, et al. Use of interleukin 15 to enhance interferon-gamma production by antigen-specific stimulated lymphocytes from rhesus macaques. J Immunol Methods. 2003;279:55-67 pubmed |
Groh V, Bruhl A, El Gabalawy H, Nelson J, Spies T. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2003;100:9452-7 pubmed |
Wang C, Liu M. Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis. Clin Exp Immunol. 2003;132:371-8 pubmed |
Ong P, Hamid Q, Travers J, Strickland I, Al Kerithy M, Boguniewicz M, et al. Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis. J Immunol. 2002;168:505-10 pubmed |
Searle R, Bromage S, Palmer J, Curry J, Lang A. Human amniotic fluid lacks interleukin-2 and interleukin-15 but can interact with the beta-chain of the interleukin-2 receptor. Immunology. 2000;99:411-7 pubmed |
Chen Y, Ting C, Peng J, Yang W, Yang K, Tsai C, et al. Restoration of cytotoxic T lymphocyte function in malignant pleural effusion: interleukin-15 vs. interleukin-2. J Interferon Cytokine Res. 2000;20:31-9 pubmed |
