Recombinant Mouse RGM-A Protein, CF | R&D Systems 2458-RG-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse RGM-A Protein, CF

catalog :

2458-RG-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Copola A, Dos Santos Í, Coutinho L, Del Bem L, de Almeida Campos Junior P, da Conceição I, et al. Transcriptomic characterization of the molecular mechanisms induced by RGMa during skeletal muscle nuclei accretion and hypertrophy. BMC Genomics. 2022;23:188 pubmed publisher
Tang S, Su B, Tao T, Yan W, Zhang R, Qin X, et al. RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells. Mol Med Rep. 2022;25: pubmed publisher
Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco L, et al. RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance. J Exp Med. 2014;211:943-59 pubmed publisher
O Leary C, Cole S, LANGFORD M, Hewage J, White A, Cooper H. RGMa regulates cortical interneuron migration and differentiation. PLoS ONE. 2013;8:e81711 pubmed publisher
Liu X, Hashimoto M, Horii H, Yamaguchi A, Naito K, Yamashita T. Repulsive guidance molecule b inhibits neurite growth and is increased after spinal cord injury. Biochem Biophys Res Commun. 2009;382:795-800 pubmed publisher
Schaffar G, Taniguchi J, Brodbeck T, Meyer A, Schmidt M, Yamashita T, et al. LIM-only protein 4 interacts directly with the repulsive guidance molecule A receptor Neogenin. J Neurochem. 2008;107:418-31 pubmed publisher
Suda M, Hata K, Sawada A, Nakamura Y, Kubo T, Yamaguchi A, et al. Peptides derived from repulsive guidance molecule act as antagonists. Biochem Biophys Res Commun. 2008;371:501-4 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2458-RG

SKU :

2458-RG-050

product name :

Recombinant Mouse RGM-A Protein, CF

Description :

The Recombinant Mouse RGM-A Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse RGM-A Protein, CF has been validated for the following applications: Binding Activity.

target :

RGM-A

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with 5% Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

Multiple bands between 25-37 kDa, reducing conditions

theoretical molecular weight :

42.5 kDa

gene symbol :

Rgma

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human BMP-4 (Catalog # 314-BP ) is coated at 1 µg/mL (100 µL/well), Recombinant Mouse RGM-A binds with an apparent Kd 50 nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q6PCX7

applications :

Binding Activity

source :

NS0-derived Recombinant Mouse RGM-A Protein

USD :

447 USD

alt names :

RGM domain family member A, RGM domain family, member A, RGMA, RGMrepulsive guidance molecule A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage