product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IFN-alpha/beta R1 Protein, CF
catalog :
245-AB-050
quantity :
50 ug
price :
443 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Harris B, Schreiter J, Chevrier M, Jordan J, Walter M. Human interferon-ϵ and interferon-κ exhibit low potency and low affinity for cell-surface IFNAR and the poxvirus antagonist B18R. J Biol Chem. 2018;293:16057-16068 pubmed publisher
product information
master code :
245-AB
SKU :
245-AB-050
product name :
Recombinant Human IFN-alpha/beta R1 Protein, CF
unit size :
50 ug
description :
The Recombinant Human IFN-alpha/beta R1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IFN-alpha/beta R1 Protein, CF has been validated for the following applications: Bioactivity.
target :
IFN-alpha/beta R1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
70-90 kDa, reducing conditions
theoretical molecular weight :
47.2 kDa
gene symbol :
IFNAR1
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human IFN-alpha/▀ R1 is present at 10 ╡g/mL, it binds to Recombinant Human IFN-alpha/▀ R2 Fc Chimera (Catalog # 4015-AB ) in the presence of recombinant human IFN-alpha 2. The concentration of Recombinant Human IFN-alpha/▀ R2 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-1.5 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
AAA52730.1
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human IFN-alpha/beta R1 protein Gly26-Lys436
source short :
NS0
USD :
443 USD
alt names :
alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFN-aR1, IFNAR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1, interferon (alpha, beta and omega) receptor 1, interferon alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, Type I interferon receptor 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.