Recombinant Human Iduronate 2-Sulfatase Protein, CF | R&D Systems 2449-SU-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Iduronate 2-Sulfatase Protein, CF

catalog :

2449-SU-020

quantity :

20 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Lamanna W, Lawrence R, Sarrazin S, Esko J. Secondary storage of dermatan sulfate in Sanfilippo disease. J Biol Chem. 2011;286:6955-62 pubmed publisher
Butler G, Dean R, Tam E, Overall C. Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding. Mol Cell Biol. 2008;28:4896-914 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

2449-SU

SKU :

2449-SU-020

product name :

Recombinant Human Iduronate 2-Sulfatase Protein, CF

description :

The Recombinant Human Iduronate 2-Sulfatase Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Iduronate 2-Sulfatase Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Iduronate 2-Sulfatase/IDS

unit size :

20 ug

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

observed molecular weight :

Multiple bands between 74-91 kDa, reducing conditions

theoretical molecular weight :

61 kDa

gene symbol :

IDS

details of functionality :

Measured by its ability to hydrolyze the substrate 4-Nitrocatechol Sulfate (PNCS). The specific activity is 1.0 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P22304

applications :

Enzyme Activity

product keywords :

2449-SU, rhIDS, hIDS, carrier-free, carrier free, 2449SU, glycobiologyenzymes, Sulfatases, Sulphatases, Iduronate 2-Sulfatase, Iduronate 2-Sulphatase, Mucopolysaccharidosis, Hunter Syndrome, Glycobiology

source :

NS0-derived Recombinant Human Iduronate 2-Sulfatase Protein, CF

USD :

447

USD 2025 :

456 USD

alt names :

Alpha-L-iduronate sulfate sulfatase, EC 3.1.6.13, iduronate 2-sulfatase, iduronate 2-sulfatase 14 kDa chain, iduronate 2-sulfatase 42 kDa chain, idursulfase, MPS2, S, SIDS

more info or order :

R&D Systems product webpage