Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF | R&D Systems 2446-CH-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF

catalog :

2446-CH-050

quantity :

50 ug

price :

432 USD

citations: 3

Reference
Starossom S, Campo Garcia J, Woelfle T, Romero Suarez S, Olah M, Watanabe F, et al. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nat Commun. 2019;10:217 pubmed publisher
Sutherland T, Rückerl D, Logan N, Duncan S, Wynn T, Allen J. Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection. PLoS Pathog. 2018;14:e1007423 pubmed publisher
Wan S, Sun X, Wu F, Yu Z, Wang L, Lin D, et al. Chi3l3: a potential key orchestrator of eosinophil recruitment in meningitis induced by Angiostrongylus cantonensis. J Neuroinflammation. 2018;15:31 pubmed publisher

product information

master code :

2446-CH

SKU :

2446-CH-050

product name :

Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF has been validated for the following applications: Bioactivity.

target :

YM1/Chitinase 3-like 3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

43 kDa, reducing conditions

theoretical molecular weight :

43 kDa

gene symbol :

Chil3

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of FaDu human squamous cell carcinoma cells. When 5 x 104 cells/well are added to Recombinant Mouse YM1/Chitinase 3-like 3 coated plates, cell adhesion is enhanced in a dose dependent manner after 1 hour incubation at 37 ░C. The ED50 for this effect is 0.3-1.2 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_034022

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse YM1/Chitinase 3-like 3 protein Met1-Tyr398, with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

AI505981, Chi3l3, Chitinase 3 like 3, Chitinase 3-like 3, ECF-L, Ym1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.