Recombinant Rat Nogo-A Fc Chimera Protein, CF | R&D Systems 2445-NG-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat Nogo-A Fc Chimera Protein, CF

catalog :

2445-NG-050

quantity :

50 ug

price :

434 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Xiao P, Gu J, Xu W, Niu X, Zhang J, Li J, et al. RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction. Autophagy. 2022;:1-20 pubmed publisher
Wright K, El Masri W, Osman A, Roberts S, Chamberlain G, Ashton B, et al. Bone marrow stromal cells stimulate neurite outgrowth over neural proteoglycans (CSPG), myelin associated glycoprotein and Nogo-A. Biochem Biophys Res Commun. 2007;354:559-66 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2445-NG

SKU :

2445-NG-050

product name :

Recombinant Rat Nogo-A Fc Chimera Protein, CF

Description :

The Recombinant Rat Nogo-A Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat Nogo-A Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Nogo-A

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

observed molecular weight :

75-85 kDa, reducing conditions

theoretical molecular weight :

46.1 kDa (monomer)

gene symbol :

Rtn4

details of functionality :

Measured by its ability to inhibit neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. Able to significantly inhibit neurite outgrowth when immobilized as a 3 µL droplet containing 300 ng on a nitrocellulose-coated microplate.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9JK11

applications :

Bioactivity

source :

NS0-derived Recombinant Rat Nogo-A Fc Chimera Protein

USD :

434 USD

alt names :

ASY;Nbla00271;Nbla10545;NI220/250;Nogo;NSP;NSP-CL;r;Reticulon-4;Rtn4;RTN4;RTN4-A;RTN4-B1;RTN4-B2;RTN4-C;RTN-X, NI220, NogoA, RTN4, RTN4A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage