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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human TGF-beta 3 Protein, CF
catalog :
243-B3-002/CF
quantity :
2 ug
price :
377 USD
more info or order :
citations: 104
Reference
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Liu G, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, et al. Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun. 2014;5:4330 pubmed publisher
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Chen P, Liu K, Hsu P, Wei C, Bai C, Ho L, et al. Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2. J Leukoc Biol. 2014;96:295-303 pubmed publisher
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Lee S, Yoon D, Paik S, Lee K, Jang Y, Lee J. microRNA-495 inhibits chondrogenic differentiation in human mesenchymal stem cells by targeting Sox9. Stem Cells Dev. 2014;23:1798-808 pubmed publisher
Zhang H, Yin Y, Wang G, Liu Z, Liu L, Sun F. Interleukin-6 disrupts blood-testis barrier through inhibiting protein degradation or activating phosphorylated ERK in Sertoli cells. Sci Rep. 2014;4:4260 pubmed publisher
Brunger J, Huynh N, Guenther C, Perez Pinera P, Moutos F, Sanchez Adams J, et al. Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci U S A. 2014;111:E798-806 pubmed publisher
Karamichos D, Funderburgh M, Hutcheon A, Zieske J, Du Y, Wu J, et al. A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells. PLoS ONE. 2014;9:e86260 pubmed publisher
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Wada N, Maeda H, Hasegawa D, Gronthos S, Bartold P, Menicanin D, et al. Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells. Stem Cells Dev. 2014;23:2225-36 pubmed publisher
Espagnolle N, Guilloton F, Deschaseaux F, Gadelorge M, Sensebe L, Bourin P. CD146 expression on mesenchymal stem cells is associated with their vascular smooth muscle commitment. J Cell Mol Med. 2014;18:104-14 pubmed publisher
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Guérit D, Philipot D, Chuchana P, Toupet K, Brondello J, Mathieu M, et al. Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells. PLoS ONE. 2013;8:e62582 pubmed publisher
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image
image 1 :
R&D Systems 243-B3-002/CF image 1
Recombinant Human TGF-beta 3 Protein Bioactivity
product information
brand :
R&D Systems
master code :
243-B3/CF
SKU :
243-B3-002/CF
product name :
Recombinant Human TGF-beta 3 Protein, CF
unit size :
2 ug
description :
The Recombinant Mouse Frizzled-9 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Frizzled-9 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
TGF-beta 3
category :
Proteins and Enzymes
alt names :
ARVD, ARVD1, FLJ16571, LDS5, RNHF, TGFB3, TGFbeta 3, TGF-beta3, TGF-beta-3, transforming growth factor beta-3, transforming growth factor, beta 3
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
all available conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
12 kDa, reducing conditions 24 kDa, non-reducing conditions
theoretical molecular weight :
12.7 kDa (monomer)
gene symbol :
TGFB3
details of functionality :
Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 0.01-0.04 ng/mL. The specific activity of recombinant human TGF-beta 3 is approximately 2.2 x 104 IU/µg, which is calibrated against recombinant human TGF-beta 3 WHO International Standard (NIBSC code: 09/234). Specific activity is for reference purposes only and is not routinely tested.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P10600
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Human TGF-beta 3 Protein, CF
extended description :
A New and Improved rh TGF-beta 3 is Now Available! It is CHO-expressed and competitively priced.
USD :
349
Jul-22 :
377 USD
product details :
A New and Improved rh TGF-beta 3 is Now Available! It is CHO-expressed and competitively priced.
sizes available :
2 ug (also 10 ug, 200 ug)
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.