Recombinant Human TGF-beta RII Protein | R&D Systems 241-R2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TGF-beta RII Protein

catalog :

241-R2

quantity :

25 ug

price :

379 USD

citations: 4

Reference
Graham J, Chamberland A, Lin Q, Li X, Dai D, Zeng W, et al. Serine protease HTRA1 antagonizes transforming growth factor-? signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation. PLoS ONE. 2013;8:e74094 pubmed publisher
Van Aarsen L, Leone D, Ho S, Dolinski B, McCoon P, Lepage D, et al. Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism. Cancer Res. 2008;68:561-70 pubmed publisher
Fazzini M, Vallejo G, Colman Lerner A, Trigo R, Campo S, Barañao J, et al. Transforming growth factor beta1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation. J Cell Physiol. 2006;207:40-8 pubmed
Rosado E, Schwartz Z, Sylvia V, Dean D, Boyan B. Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways. Biochim Biophys Acta. 2002;1590:1-15 pubmed

product information

brand :

R&D Systems

master code :

241-R2

SKU :

241-R2-025

product name :

Recombinant Human TGF-beta RII Protein

description :

The Recombinant Human TGF-beta RII Protein from R&D Systems is derived from NS0. The Recombinant Human TGF-beta RII Protein has been validated for the following applications: Bioactivity.

target :

TGF-beta RII

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

Multiple bands between 20-35 kDa, reducing conditions

theoretical molecular weight :

15 kDa

gene symbol :

TGFBR2

details of functionality :

Measured by its ability to inhibit TGF-beta 1 activity on HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 1-3 µg/mL in the presence of 0.25 ng/mL of recombinant human TGF-beta 1.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

241-R2

accessionNumbers :

P37173.2

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human TGF-beta RII protein Ile24-Asp159

2020 USD :

379

2021 USD :

379 USD

alt names :

AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.