Recombinant Human SREC-I/SCARF1 Fc Chimera Protein, CF | R&D Systems 2409-SR-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human SREC-I/SCARF1 Fc Chimera Protein, CF

catalog :

2409-SR-050

quantity :

50 ug

price :

523 USD

citations: 5

Reference
Patten D, Kamarajah S, Rose J, Tickle J, Shepherd E, Adams D, et al. SCARF-1 promotes adhesion of CD4+ T cells to human hepatic sinusoidal endothelium under conditions of shear stress. Sci Rep. 2017;7:17600 pubmed publisher
BiedroÅ„ R, KonopiÅ„ski M, Marcinkiewicz J, JÃ³zefowski S. Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. PLoS ONE. 2015;10:e0123293 pubmed publisher
Baur S, Rautenberg M, Faulstich M, Faulstich M, Grau T, Severin Y, et al. A nasal epithelial receptor for Staphylococcus aureus WTA governs adhesion to epithelial cells and modulates nasal colonization. PLoS Pathog. 2014;10:e1004089 pubmed publisher
Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood. 2010;116:3099-107 pubmed publisher
Narazaki M, Segarra M, Tosato G. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A. Blood. 2008;111:4126-36 pubmed publisher

product information

master code :

2409-SR

SKU :

2409-SR-050

product name :

Recombinant Human SREC-I/SCARF1 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human SREC-I/SCARF1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human SREC-I/SCARF1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

SREC-I/SCARF1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

100 kDa, reducing conditions

theoretical molecular weight :

69.1 kDa (monomer)

gene symbol :

SCARF1

details of functionality :

Measured by its binding ability in a functional ELISA. When Human AcLDL is immobilized at 2 ╡g/mL (100 ╡L/well), Recombinant Human SREC-I/SCARF1 Fc Chimera (Catalog # 2409-SR) binds with an ED50 of 5.00-50.0 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q14162

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human SREC-I/SCARF1 protein Human SREC-I (Ser20-Thr421) Accession # Q14162 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

523 USD

alt names :

Acetyl LDL receptor, KIAA0149endothelial cells scavenger receptor, MGC47738, SCARF1, scavenger receptor class F, member 1, Scavenger receptor expressed by endothelial cells 1, SREC1, SRECI, SREC-I, SRECscavenger receptor expressed by endothelial cells, SR-F1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.