product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD38 Protein, CF
catalog :
2404-AC-010
quantity :
10 ug
price :
388 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Yaku K, Palikhe S, Izumi H, Yoshida T, Hikosaka K, Hayat F, et al. BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities. Nat Commun. 2021;12:6767 pubmed publisher
Wang E, Mao T, Klein J, Dai Y, Huck J, Liu F, et al. Diverse Functional Autoantibodies in Patients with COVID-19. medRxiv. 2020;: pubmed publisher
Escande C, Nin V, Price N, Capellini V, Gomes A, Barbosa M, et al. Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome. Diabetes. 2013;62:1084-93 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
2404-AC
SKU :
2404-AC-010
product name :
Recombinant Human CD38 Protein, CF
Description :
The Recombinant Human CD38 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD38 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
CD38
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in MES and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
43 kDa, reducing conditions
theoretical molecular weight :
31 kDa
gene symbol :
CD38
details of functionality :
Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDP-ribose. Graeff, R.M. et al . (1994) J. Biol. Chem. 269 :30260. The specific activity is 2,500 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P28907
applications :
Enzyme Activity
source :
NS0-derived Recombinant Human CD38 Protein
USD :
388 USD
alt names :
2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20), 2'-phospho-cyclic-ADP-ribose transferase, ADPRC 1, ADPRC1, ADP-ribosyl Cyclase, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, CD_antigen: CD38, CD38, CD38 antigen, CD38 antigen (p45), CD38 molecule, cluster of differentiation 38, Cyclic ADP-ribose Hydrolase, Cyclic ADP-ribose hydrolase 1, EC 2.4.99.20, EC 3.2.2.6, EC:3.2.2.6, NAD(+) nucleosidase, T10
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.