Recombinant Human TGF-beta 1 GMP Protein, CF | R&D Systems 240-GMP-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human TGF-beta 1 GMP Protein, CF

catalog :

240-GMP-010

quantity :

10 ug

price :

1187 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Bayram B, Owen A, Dudakovic A, Dagneaux L, Turner T, Bettencourt J, et al. A Potential Theragnostic Regulatory Axis for Arthrofibrosis Involving Adiponectin (ADIPOQ) Receptor 1 and 2 (ADIPOR1 and ADIPOR2), TGFβ1, and Smooth Muscle α-Actin (ACTA2). J Clin Med. 2020;9: pubmed publisher
Yamashita K, Hatou S, Inagaki E, Higa K, Tsubota K, Shimmura S. A Rabbit Corneal Endothelial Dysfunction Model Using Endothelial-Mesenchymal Transformed Cells. Sci Rep. 2018;8:16868 pubmed publisher

image

image 1 :

Recombinant Human TGF-beta 1 GMP Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

240-GMP

SKU :

240-GMP-010

product name :

Recombinant Human TGF-beta 1 GMP Protein, CF

Description :

The Recombinant Human TGF-beta 1 GMP Protein, CF from R&D Systems is derived from CHO. The Recombinant Human TGF-beta 1 GMP Protein, CF has been validated for the following applications: Bioactivity.

target :

TGF-beta 1

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE with silver staining.

species :

Human

observed molecular weight :

12 kDa, reducing conditions 24 kDa, non-reducing conditions

theoretical molecular weight :

12.8 kDa (monomer)

gene symbol :

TGFB1

details of functionality :

Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 0.04-0.2 ng/mL. The specific activity of recombinant human TGF-beta 1 GMP is 1.0 x 107 units/mg, which is calibrated against the human TGF-beta 1 Standard (NIBSC code: 89/514).

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P01137.2

applications :

Bioactivity

source :

CHO-derived Recombinant Human TGF-beta 1 GMP Protein

USD :

1187 USD

alt names :

CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1, TGFB, TGFB1, TGFbeta, TGFbeta 1, TGF-beta 1 protein, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at <= -20 °C as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage