Recombinant Human FGF-6 Protein | R&D Systems 238-F6-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-6 Protein

catalog :

238-F6-025

quantity :

25 ug

price :

327 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Parthasarathy G, Pattison M, Midkiff C. The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi: likely intersectionality with other neurological conditions. J Neuroinflammation. 2023;20:10 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher
Israeli D, Benchaouir R, Ziaei S, Rameau P, Gruszczynski C, Peltekian E, et al. FGF6 mediated expansion of a resident subset of cells with SP phenotype in the C2C12 myogenic line. J Cell Physiol. 2004;201:409-19 pubmed
Ropiquet F, Giri D, Kwabi Addo B, Mansukhani A, Ittmann M. Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Res. 2000;60:4245-50 pubmed

product information

master code :

238-F6

SKU :

238-F6-025

product name :

Recombinant Human FGF-6 Protein

unit size :

25 ug

description :

The Recombinant Human FGF-6 Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF-6 Protein has been validated for the following applications: Bioactivity.

target :

FGF-6

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and CHAPS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

15-22 kDa, reducing conditions

theoretical molecular weight :

19 kDa (Gly41 - Ile208) 16 kDa (Gly67 - Ile208)

gene symbol :

FGF6

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.1-0.3 ng/mL in the presence of 1 ╡g/mL of heparin.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P10767.4

applications :

Bioactivity

source long :

E. coli -derived human FGF-6 protein Gly41-Ile208

source short :

E. coli

USD :

327 USD

alt names :

FGF6, FGF-6, fibroblast growth factor 6, HBGF-6, Heparin secretory-transforming protein 2, Heparin-binding growth factor 6, HST2, HST-2, HSTF2, HSTF-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage