product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-22BP Fc Chimera Protein, CF
catalog :
2376-BP-025
quantity :
25 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Nakagome K, Imamura M, Kawahata K, Harada H, Okunishi K, Matsumoto T, et al. High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism. J Immunol. 2011;187:5077-89 pubmed publisher
product information
master code :
2376-BP
SKU :
2376-BP-025
product name :
Recombinant Mouse IL-22BP Fc Chimera Protein, CF
unit size :
25 ug
description :
The Recombinant Mouse IL-22BP Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse IL-22BP Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
IL-22BP
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
60-70 kDa, reducing conditions
theoretical molecular weight :
51.8 kDa (monomer)
details of functionality :
Measured by its ability to inhibit IL-22-induced IL-10 secretion by COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is 1-4 ╡g/mL in the presence of 0.5 ng/mL of Recombinant Mouse IL-22 (Catalog # 582-ML ).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q08AV1
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived mouse IL-22BP protein Mouse IL-22BP (Thr19-Pro230) Accession # Q08AV1 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
456 USD
alt names :
class II cytokine receptor, CRF2-10, CRF2-S1IL22BP, CRF2-X, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, Cytokine receptor family type 2, soluble 1, IL-22 RA2, IL-22 receptor subunit alpha-2, IL22BP, IL-22BPCRF2X, IL22RA2, IL-22RA2, IL-22R-alpha-2, interleukin 22 receptor, alpha 2, interleukin 22-binding protein, interleukin-22 receptor subunit alpha-2, Interleukin-22-binding protein, MGC150509, MGC150510, zcytoR16
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.