product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGF-5 Protein
catalog :
237-F5-050
quantity :
50 ug
price :
237 USD
more info or order :
citations: 4
Reference
Tang Y, Xiong S, Yu P, Liu F, Cheng L. Direct Conversion of Mouse Fibroblasts into Neural Stem Cells by Chemical Cocktail Requires Stepwise Activation of Growth Factors and Nup210. Cell Rep. 2018;24:1355-1362.e3 pubmed publisher
Higgins C, Petukhova L, Harel S, Ho Y, Drill E, Shapiro L, et al. FGF5 is a crucial regulator of hair length in humans. Proc Natl Acad Sci U S A. 2014;111:10648-53 pubmed publisher
Di Maggio N, Mehrkens A, Papadimitropoulos A, Schaeren S, Heberer M, Banfi A, et al. Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem Cells. 2012;30:1455-64 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher
product information
brand :
R&D Systems
master code :
237-F5
SKU :
237-F5-050
product name :
Recombinant Human FGF-5 Protein
description :
The Recombinant Human FGF-5 Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF-5 Protein has been validated for the following applications: Bioactivity.
target :
FGF-5
category :
Proteins and Enzymes
sizes available :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4, EDTA and DTT with Trehalose and with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
theoretical molecular weight :
27 kDa
gene symbol :
FGF5
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 2-10 ng/mL in the presence of 1 µg/mL of heparin.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q8NF90
applications :
Bioactivity
source :
E. coli-derived Recombinant Human FGF-5 Protein
USD :
237
USD 2023 :
237 USD
alt names :
FGF5, FGF-5, fibroblast growth factor 5, HBGF-5, Heparin-binding growth factor 5, Smag-82
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.