Recombinant Human FGF-5 Protein, CF | R&D Systems 237-F5-050/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-5 Protein, CF

catalog :

237-F5-050/CF

quantity :

50 ug

price :

256 USD

citations: 6

Reference
Daneshpour H, van den Bersselaar P, Chao C, Fazzio T, Youk H. Macroscopic quorum sensing sustains differentiating embryonic stem cells. Nat Chem Biol. 2023;19:596-606 pubmed publisher
Park J, Choi J, Cao L, Mohanty J, Suzuki Y, Park A, et al. Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein. Cell Rep. 2022;41:111545 pubmed publisher
Tang Y, Xiong S, Yu P, Liu F, Cheng L. Direct Conversion of Mouse Fibroblasts into Neural Stem Cells by Chemical Cocktail Requires Stepwise Activation of Growth Factors and Nup210. Cell Rep. 2018;24:1355-1362.e3 pubmed publisher
Higgins C, Petukhova L, Harel S, Ho Y, Drill E, Shapiro L, et al. FGF5 is a crucial regulator of hair length in humans. Proc Natl Acad Sci U S A. 2014;111:10648-53 pubmed publisher
Di Maggio N, Mehrkens A, Papadimitropoulos A, Schaeren S, Heberer M, Banfi A, et al. Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c. Stem Cells. 2012;30:1455-64 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher

product information

master code :

237-F5/CF

SKU :

237-F5-050/CF

product name :

Recombinant Human FGF-5 Protein, CF

unit size :

50 ug

description :

The Recombinant Human FGF-5 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF-5 Protein, CF has been validated for the following applications: Bioactivity.

target :

FGF-5

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in MOPS, Na2SO4, EDTA and DTT.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

27 kDa

gene symbol :

FGF5

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 2-10 ng/mL in the presence of 1 ╡g/mL of heparin.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q8NF90

applications :

Bioactivity

source long :

E. coli -derived human FGF-5 protein Glu23-Gly268 (Lys238Asn and Pro245Ser), with an N-terminal Met & Leu26-Gly268 (Lys238Asn and Pro245Ser)

source short :

E. coli

USD :

256 USD

alt names :

FGF5, FGF-5, fibroblast growth factor 5, HBGF-5, Heparin-binding growth factor 5, Smag-82

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening.