product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Ficolin-3 Protein, CF
catalog :
2367-FC-050
quantity :
50 ug
price :
476 USD
more info or order :
citations: 5
Reference
Jang H, Jun Y, Kim S, Kim E, Jung Y, Park B, et al. FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress. Cell Death Dis. 2021;12:407 pubmed publisher
Wolf D, Anto Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann J, et al. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nat Commun. 2018;9:525 pubmed publisher
Man Kupisinska A, Michalski M, Maciejewska A, Swierzko A, Cedzynski M, Lugowski C, et al. A New Ligand-Based Method for Purifying Active Human Plasma-Derived Ficolin-3 Complexes Supports the Phenomenon of Crosstalk between Pattern-Recognition Molecules and Immunoglobulins. PLoS ONE. 2016;11:e0156691 pubmed publisher
Michalski M, St Swierzko A, Lukasiewicz J, Man Kupisinska A, Karwaciak I, Przygodzka P, et al. Ficolin-3 activity towards the opportunistic pathogen, Hafnia alvei. Immunobiology. 2015;220:117-23 pubmed publisher
Swierzko A, Lukasiewicz J, Cedzynski M, Maciejewska A, Jachymek W, Niedziela T, et al. New functional ligands for ficolin-3 among lipopolysaccharides of Hafnia alvei. Glycobiology. 2012;22:267-80 pubmed publisher
product information
brand :
R&D Systems
master code :
2367-FC
SKU :
2367-FC-050
product name :
Recombinant Human Ficolin-3 Protein, CF
description :
The Recombinant Human Ficolin-3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Ficolin-3 Protein, CF has been validated for the following applications: Binding Activity.
target :
Ficolin-3
category :
Proteins and Enzymes
sizes available :
50 ug
buffer :
Supplied as a 0.2 µm filtered solution in PBS and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
37 kDa, reducing conditions
theoretical molecular weight :
30.7 kDa
gene symbol :
FCN3
details of functionality :
Measured by its ability to bind biotinylated a-D-Mannose-Polyacrylamide in a functional ELISA.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
O75636-1
applications :
Binding Activity
source :
NS0-derived Recombinant Human Ficolin-3 Protein, CF
USD :
453
USD 2023 :
476 USD
alt names :
FCN3, FCNH, Ficolin3, HAKA1, H-Ficolin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -20 to -70 °C under sterile conditions after opening.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.