Recombinant Human Ficolin-3 Protein, CF | R&D Systems 2367-FC-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Ficolin-3 Protein, CF

catalog :

2367-FC-050

quantity :

50 ug

price :

541 USD

citations: 6

Reference
Delli xe8 re S, Chauvin C, Wong S, Gressler M, Possetti V, Parente R, et al. Interplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus. Nat Commun. 2024;15:6966 pubmed publisher
Jang H, Jun Y, Kim S, Kim E, Jung Y, Park B, et al. FCN3 functions as a tumor suppressor of lung adenocarcinoma through induction of endoplasmic reticulum stress. Cell Death Dis. 2021;12:407 pubmed publisher
Wolf D, Anto Michel N, Blankenbach H, Wiedemann A, Buscher K, Hohmann J, et al. A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nat Commun. 2018;9:525 pubmed publisher
Man Kupisinska A, Michalski M, Maciejewska A, Swierzko A, Cedzynski M, Lugowski C, et al. A New Ligand-Based Method for Purifying Active Human Plasma-Derived Ficolin-3 Complexes Supports the Phenomenon of Crosstalk between Pattern-Recognition Molecules and Immunoglobulins. PLoS ONE. 2016;11:e0156691 pubmed publisher
Michalski M, St Swierzko A, Lukasiewicz J, Man Kupisinska A, Karwaciak I, Przygodzka P, et al. Ficolin-3 activity towards the opportunistic pathogen, Hafnia alvei. Immunobiology. 2015;220:117-23 pubmed publisher
Swierzko A, Lukasiewicz J, Cedzynski M, Maciejewska A, Jachymek W, Niedziela T, et al. New functional ligands for ficolin-3 among lipopolysaccharides of Hafnia alvei. Glycobiology. 2012;22:267-80 pubmed publisher

product information

master code :

2367-FC

SKU :

2367-FC-050

product name :

Recombinant Human Ficolin-3 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Ficolin-3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Ficolin-3 Protein, CF has been validated for the following applications: Binding Activity.

target :

Ficolin-3

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in PBS and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

37 kDa, reducing conditions

theoretical molecular weight :

30.7 kDa

gene symbol :

FCN3

details of functionality :

Measured by its ability to bind biotinylated a-D-Mannose-Polyacrylamide in a functional ELISA.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O75636-1

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human Ficolin-3 protein Lys22-Arg299, with a C-terminal 10-His tag

source short :

NS0

USD :

541 USD

alt names :

FCN3, FCNH, Ficolin3, HAKA1, H-Ficolin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, -20 to -70 ░C under sterile conditions after opening.