Recombinant Human Endorepellin Protein, CF | R&D Systems 2364-ER-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Endorepellin Protein, CF

catalog :

2364-ER-050

quantity :

50 ug

price :

575 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Provenzale I, De Simone I, Gibbins J, Heemskerk J, van der Meijden P, Jones C. Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan. Int J Mol Sci. 2023;24: pubmed publisher
Katt M, Linville R, Mayo L, Xu Z, Searson P. Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation. Fluids Barriers CNS. 2018;15:7 pubmed publisher
Toda M, Ueno M, Yamada J, Hiraga A, Tanaka H, Schlötzer Schrehardt U, et al. The Different Binding Properties of Cultured Human Corneal Endothelial Cell Subpopulations to Descemet's Membrane Components. Invest Ophthalmol Vis Sci. 2016;57:4599-605 pubmed publisher

image

image 1 :

Recombinant Human Endorepellin Protein Binding Activity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

2364-ER

SKU :

2364-ER-050

product name :

Recombinant Human Endorepellin Protein, CF

Description :

The Recombinant Human Endorepellin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Endorepellin Protein, CF has been validated for the following applications: Bioactivity.

target :

Endorepellin/Perlecan

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

90-95 kDa, reducing conditions

theoretical molecular weight :

76.7 kDa

gene symbol :

HSPG2

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human VEGF R1/Flt-1 (Catalog # 321-FL ) is coated at 5 µg/mL (100 µL/well), the concentration of Recombinant Human Endorepellin/Perlecan that produces 50% of the optimal binding response is approximately 0.75-6 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P98160

applications :

Bioactivity

source :

NS0-derived Recombinant Human Endorepellin Protein

USD :

575 USD

alt names :

basement membrane-specific heparan sulfate proteoglycan core protein, endorepellin (domain V region), heparan sulfate proteoglycan 2, HSPG, perlecan, perlecan proteoglycan, PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia), PRCAN, SJA, SJS, SJS1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage