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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGF-4 Protein
catalog :
235-F4-025
quantity :
25 ug
price :
302 USD
more info or order :
citations: 56
Reference
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Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
Workman M, Gleeson J, Troisi E, Estrada H, Kerns S, HINOJOSA C, et al. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips. Cell Mol Gastroenterol Hepatol. 2018;5:669-677.e2 pubmed publisher
Okamoto R, Takayama K, Akita N, Nagamoto Y, Hosokawa D, Iizuka S, et al. Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B. Cell Transplant. 2018;27:299-309 pubmed publisher
Fagg W, Liu N, Yang M, Cheng K, Chung E, Kim J, et al. Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver. Cell Transplant. 2017;26:1868-1877 pubmed publisher
Múnera J, Sundaram N, Rankin S, Hill D, Watson C, Mahe M, et al. Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell Stem Cell. 2017;21:51-64.e6 pubmed publisher
Kang M, Garg V, Hadjantonakis A. Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2. Dev Cell. 2017;41:496-510.e5 pubmed publisher
Mitani S, Takayama K, Nagamoto Y, Imagawa K, Sakurai F, Tachibana M, et al. Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling. Mol Ther. 2017;25:1420-1433 pubmed publisher
Hanker A, Garrett J, Estrada M, Moore P, Ericsson P, Koch J, et al. HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2. Clin Cancer Res. 2017;23:4323-4334 pubmed publisher
Elberry D, Amin S, Esmail R, Rashed L, Gamal M. Effect of undifferentiated versus hepatogenic partially differentiated mesenchymal stem cells on hepatic and cognitive functions in liver cirrhosis. EXCLI J. 2016;15:652-670 pubmed publisher
Holmes D, Heine V. Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open. 2017;6:402-406 pubmed publisher
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Saiz N, Williams K, Seshan V, Hadjantonakis A. Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst. Nat Commun. 2016;7:13463 pubmed publisher
Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
Morrison G, Scognamiglio R, Trumpp A, Smith A. Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification. EMBO J. 2016;35:356-68 pubmed publisher
Tamminen K, Balboa D, Toivonen S, Pakarinen M, Wiener Z, Alitalo K, et al. Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1. PLoS ONE. 2015;10:e0134551 pubmed publisher
Tabata T, Petitt M, Zydek M, Fang Hoover J, Larocque N, Tsuge M, et al. Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta. J Virol. 2015;89:5134-47 pubmed publisher
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Watanabe H, Takayama K, Inamura M, Tachibana M, Mimura N, Katayama K, et al. HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin. PLoS ONE. 2014;9:e90791 pubmed publisher
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image
image 1 :
R&D Systems 235-F4-025 image 1
Recombinant Human FGF-4 Protein Bioactivity
product information
brand :
R&D Systems
master code :
235-F4
SKU :
235-F4-025
product name :
Recombinant Human FGF-4 Protein
unit size :
25 ug
description :
The Recombinant Human FGF-4 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF-4 Protein, CF has been validated for the following applications: Bioactivity.
target :
FGF-4
category :
Proteins and Enzymes
alt names :
FGF4, fibroblast growth factor 4, HBGF-4, HBGF-4Transforming protein KS3, heparin secretory transforming protein 1, Heparin secretory-transforming protein 1, Heparin-binding growth factor 4, HST-1, HST-1HSTF-1, HSTF1fibroblast growth factor 4 splice isoform, HSTFGF-4, human stomach cancer, transforming factor from FGF-related oncogene, kaposi sarcoma oncogene, KFGF, K-FGF, KS3, oncogene HST
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
all available conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
16 kDa, reducing conditions
theoretical molecular weight :
17 kDa
gene symbol :
FGF4
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.25-1.25 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P08620
applications :
Bioactivity
source :
E. coli-derived Recombinant Human FGF-4 Protein
extended description :
A New and Improved rh FGF-4 is Now Available! It has enhanced purity!
USD :
279
Jul-22 :
302 USD
product details :
A New and Improved rh FGF-4 is Now Available! It has enhanced purity!
sizes available :
25 ug (also 1 mg)
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.