Human Vitronectin Protein, CF | R&D Systems 2349-VN-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Human Vitronectin Protein, CF

catalog :

2349-VN-100

quantity :

100 ug

price :

310 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Song Y, Jamali N, Sorenson C, Sheibani N. Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells. Cells. 2023;12: pubmed publisher
Price J, Azizi E, Naiche L, Parvani J, Shukla P, Kim S, et al. Notch3 signaling promotes tumor cell adhesion and progression in a murine epithelial ovarian cancer model. PLoS ONE. 2020;15:e0233962 pubmed publisher
Karpova D, Rettig M, Ritchey J, Cancilla D, Christ S, Gehrs L, et al. Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. J Clin Invest. 2019;129:2745-2759 pubmed publisher
Yamamoto Y, Miyazaki S, Maruyama K, Kobayashi R, Le M, Kano A, et al. Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. PLoS ONE. 2018;13:e0201960 pubmed publisher
Hanson A, Gambill J, Phomakay V, Staten C, Kelley M. 9-cis-retinoic Acid and troglitazone impacts cellular adhesion, proliferation, and integrin expression in K562 cells. PLoS ONE. 2014;9:e93005 pubmed publisher
Lou Y, Kanninen L, Kuisma T, Niklander J, Noon L, Burks D, et al. The use of nanofibrillar cellulose hydrogel as a flexible three-dimensional model to culture human pluripotent stem cells. Stem Cells Dev. 2014;23:380-92 pubmed publisher
Tumbarello D, Temple J, Brenton J. ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells. Mol Cancer. 2012;11:36 pubmed publisher
Franco M, Roswall P, Cortez E, Hanahan D, Pietras K. Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression. Blood. 2011;118:2906-17 pubmed publisher

product information

brand :

R&D Systems

master code :

2349-VN

SKU :

2349-VN-100

product name :

Human Vitronectin Protein, CF

unit size :

100 ug

seo description :

The Human Vitronectin Protein, CF from R&D Systems is derived from Human Plasma. The Human Vitronectin Protein, CF has been validated for the following applications: Bioactivity.

target :

Vitronectin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and Urea.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

55-85 kDa, reducing conditions

gene symbol :

VTN

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of DU145 human prostate carcinoma cells or B16-F1 mouse melanoma cells. When 5 x 104 cells/well are added to Vitronectin coated plates (5 ╡g/mL with 100 ╡L/well), approximately 55% will adhere after 30 minutes at 37 ░C. Optimal concentration depends on cell type as well as the application or research objectives.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

applications :

Bioactivity

source :

Human Plasma

USD :

310 USD

alt names :

complement S-protein, epibolin, serum spreading factor, Serum-spreading factor, somatomedin B, S-protein, V75, vitronectin, vitronectin (serum spreading factor, somatomedin B, complement S-protein), VN, VNT, VTN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage