Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein | R&D Systems 234-FSE-025 product information

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product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein

catalog :

234-FSE-025

quantity :

25 ug

price :

297 USD

citations: 14

Reference
Cervantes Villagrana R, Mendoza V, Hinck C, de la Fuente Le xf3 n R, Hinck A, Reyes Cruz G, et al. Betaglycan sustains HGF/Met signaling in lung cancer and endothelial cells promoting cell migration and tumor growth. Heliyon. 2024;10:e30520 pubmed publisher
Shabani K, Pigeon J, Benaissa Touil Zariouh M, Liu T, Saffarian A, Komatsu J, et al. The temporal balance between self-renewal and differentiation of human neural stem cells requires the amyloid precursor protein. Sci Adv. 2023;9:eadd5002 pubmed publisher
Hermans F, Hemeryck L, Bueds C, Torres Pereiro M, Hasevoets S, Kobayashi H, et al. Organoids from mouse molar and incisor as new tools to study tooth-specific biology and development. Stem Cell Reports. 2023;18:1166-1181 pubmed publisher
Kim J, Lim I, Park C, Joo H, Noh J, Choi S, et al. Thymosin β4-Enhancing Therapeutic Efficacy of Human Adipose-Derived Stem Cells in Mouse Ischemic Hindlimb Model. Int J Mol Sci. 2020;21: pubmed publisher
Qi J, Bell B, Singh R, Batoki J, Wolk A, Cutler A, et al. Sorsby Fundus Dystrophy Mutation in Tissue Inhibitor of Metalloproteinase 3 (TIMP3) promotes Choroidal Neovascularization via a Fibroblast Growth Factor-dependent Mechanism. Sci Rep. 2019;9:17429 pubmed publisher
Menguy T, Briaux A, Jeunesse E, Giustiniani J, Calcei A, Guyon T, et al. Anti-CD160, Alone or in Combination With Bevacizumab, Is a Potent Inhibitor of Ocular Neovascularization in Rabbit and Monkey Models. Invest Ophthalmol Vis Sci. 2018;59:2687-2698 pubmed publisher
Li M, Zhao X, Wang W, Shi H, Pan Q, Lu Z, et al. Ythdf2-mediated m6A mRNA clearance modulates neural development in mice. Genome Biol. 2018;19:69 pubmed publisher
KjartansdÃ³ttir K, Reda A, Panula S, Day K, Hultenby K, SÃ¶der O, et al. A Combination of Culture Conditions and Gene Expression Analysis Can Be Used to Investigate and Predict hES Cell Differentiation Potential towards Male Gonadal Cells. PLoS ONE. 2015;10:e0144029 pubmed publisher
Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. J Pharmacol Exp Ther. 2014;349:209-20 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Ghosh J, Shenoy A, Clark J. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry. 2007;46:6308-17 pubmed
Li F, Shetty A, Sugahara K. Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways. J Biol Chem. 2007;282:2956-66 pubmed
Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal P, Pesce M, et al. Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential. Am J Pathol. 2006;169:1167-82 pubmed
Otterdal K, Smith C, Oie E, Pedersen T, Yndestad A, Stang E, et al. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood. 2006;108:928-35 pubmed

product information

master code :

234-FSE

SKU :

234-FSE-025

product name :

Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein

unit size :

25 ug

description :

The Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein has been validated for the following applications: Bioactivity.

target :

FGF basic/FGF2/bFGF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-HCl and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

17.4 kDa

gene symbol :

FGF2

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.5-2.5 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein Bioactivity

accessionNumbers :

NP_001997

applications :

Bioactivity

source long :

E. coli -derived human FGF basic/FGF2/bFGF protein Gly132-Ser288

source short :

E. coli

USD :

297 USD

alt names :

Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF2, FGF-2, FGFBprostatropin, fibroblast growth factor 2 (basic), HBGF-2, heparin-binding growth factor 2, Prostatropin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.