product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein, CF
catalog :
234-FSE-025/CF
quantity :
25 ug
price :
297 USD
more info or order :
citations: 11
Reference
Kim J, Lim I, Park C, Joo H, Noh J, Choi S, et al. Thymosin β4-Enhancing Therapeutic Efficacy of Human Adipose-Derived Stem Cells in Mouse Ischemic Hindlimb Model. Int J Mol Sci. 2020;21: pubmed publisher
Qi J, Bell B, Singh R, Batoki J, Wolk A, Cutler A, et al. Sorsby Fundus Dystrophy Mutation in Tissue Inhibitor of Metalloproteinase 3 (TIMP3) promotes Choroidal Neovascularization via a Fibroblast Growth Factor-dependent Mechanism. Sci Rep. 2019;9:17429 pubmed publisher
Menguy T, Briaux A, Jeunesse E, Giustiniani J, Calcei A, Guyon T, et al. Anti-CD160, Alone or in Combination With Bevacizumab, Is a Potent Inhibitor of Ocular Neovascularization in Rabbit and Monkey Models. Invest Ophthalmol Vis Sci. 2018;59:2687-2698 pubmed publisher
Li M, Zhao X, Wang W, Shi H, Pan Q, Lu Z, et al. Ythdf2-mediated m6A mRNA clearance modulates neural development in mice. Genome Biol. 2018;19:69 pubmed publisher
Kjartansdóttir K, Reda A, Panula S, Day K, Hultenby K, Söder O, et al. A Combination of Culture Conditions and Gene Expression Analysis Can Be Used to Investigate and Predict hES Cell Differentiation Potential towards Male Gonadal Cells. PLoS ONE. 2015;10:e0144029 pubmed publisher
Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis. J Pharmacol Exp Ther. 2014;349:209-20 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Ghosh J, Shenoy A, Clark J. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry. 2007;46:6308-17 pubmed
Li F, Shetty A, Sugahara K. Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways. J Biol Chem. 2007;282:2956-66 pubmed
Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal P, Pesce M, et al. Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential. Am J Pathol. 2006;169:1167-82 pubmed
Otterdal K, Smith C, Oie E, Pedersen T, Yndestad A, Stang E, et al. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood. 2006;108:928-35 pubmed
product information
brand :
R&D Systems
master code :
234-FSE/CF
SKU :
234-FSE-025/CF
product name :
Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein, CF
unit size :
25 ug
seo description :
The Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein, CF has been validated for the following applications: Bioactivity.
target :
FGF basic/FGF2/bFGF
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris-HCl and NaCl.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
17.4 kDa
gene symbol :
FGF2
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.5-2.5 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein Bioactivity
accessionNumbers :
NP_001997
applications :
Bioactivity
source :
E. coli-derived Recombinant Human FGF basic/FGF2/bFGF (157 aa) Protein, CF
USD :
297 USD
alt names :
Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF2, FGF-2, FGFBprostatropin, fibroblast growth factor 2 (basic), HBGF-2, heparin-binding growth factor 2, Prostatropin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.