Recombinant Human Coagulation Factor III/Tissue Factor, CF | R&D Systems 2339-PA-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Coagulation Factor III/Tissue Factor, CF

catalog :

2339-PA-010

quantity :

10 ug

price :

432 USD

citations: 6

Reference
Suzuki A, Hamada S, Oono A, Hasegawa Y, Yamauchi Y, Okishige K, et al. Edoxaban eliminates hypercoagulability evoked by transient temperature changes in human whole blood. J Arrhythm. 2023;39:901-908 pubmed publisher
Rees P, Castle J, Clouston H, Lamb R, Singh U, Duff S, et al. The effects of coagulation factors and their inhibitors on proliferation and migration in colorectal cancer. Cancer Med. 2023;12:17184-17192 pubmed publisher
Feng Y, Ma J, Tang L, Lin W, Tao Y, Cheng Z, et al. Characterization of a Missense Mutation in the Catalytic Domain and a Splicing Mutation of Coagulation Factor X Compound Heterozygous in a Chinese Pedigree. Genes (Basel). 2021;12: pubmed publisher
Holt R, Luo D, Gruver N, Khismatullin D. Quasi-static acoustic tweezing thromboelastometry. J Thromb Haemost. 2017;15:1453-1462 pubmed publisher
Conroy A, Liles W, Molyneux M, Rogerson S, Kain K. Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi. PLoS ONE. 2011;6:e28540 pubmed publisher
Amara U, Flierl M, Rittirsch D, Klos A, Chen H, Acker B, et al. Molecular intercommunication between the complement and coagulation systems. J Immunol. 2010;185:5628-36 pubmed publisher

product information

master code :

2339-PA

SKU :

2339-PA-010

product name :

Recombinant Human Coagulation Factor III/Tissue Factor, CF

unit size :

10 ug

description :

The Recombinant Human Coagulation Factor III/Tissue Factor, CF from R&D Systems is derived from NS0. The Recombinant Human Coagulation Factor III/Tissue Factor, CF has been validated for the following applications: Enzyme Activity.

target :

Coagulation Factor III/Tissue Factor

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

41 kDa and 43 kDa, reducing conditions

theoretical molecular weight :

26 kDa

gene symbol :

details of functionality :

Measured by its ability to activate Coagulation Factor VII in cleaving a fluorogenic peptide substrate Boc-VPR-AMC (Catalog # ES011 ). The AC50 is 4.0 ╡g/mL, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P13726

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human Coagulation Factor III/Tissue Factor protein Gly34-Glu251, with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

CD142, CD142 antigen, Coagulation factor III, coagulation factor III (thromboplastin, tissue factor), F3, FLJ17960, TF, TFA, Thromboplastin, tissue factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.