Recombinant Human Kallikrein 1 Protein, CF | R&D Systems 2337-SE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Kallikrein 1 Protein, CF

catalog :

2337-SE-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Bosc E, Anastasie J, Soualmia F, Coric P, Kim J, Wang L, et al. Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics. Cell Death Dis. 2022;13:959 pubmed publisher
Guillon Munos A, Oikonomopoulou K, Michel N, Smith C, Petit Courty A, Canepa S, et al. Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors. J Biol Chem. 2011;286:25505-18 pubmed publisher
Kantyka T, Fischer J, Wu Z, Declercq W, Reiss K, Schroder J, et al. Inhibition of kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6. Peptides. 2011;32:1187-92 pubmed publisher
Sexton D, Chen T, Martik D, Kuzmic P, Kuang G, Chen J, et al. Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases. Biochem J. 2009;422:383-92 pubmed publisher

product information

brand :

R&D Systems

master code :

2337-SE

SKU :

2337-SE-010

product name :

Recombinant Human Kallikrein 1 Protein, CF

unit size :

10 ug

seo description :

The Recombinant Human Kallikrein 1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Kallikrein 1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Kallikrein 1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and CaCl2.

conjugate :

Unconjugated

dilution :

Enzyme Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

41 kDa, 45 kDa, 49 kDa and 56 kDa, reducing conditions

theoretical molecular weight :

32 kDa

gene symbol :

KLK1

details of functionality :

Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is 1,500 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_002248

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Kallikrein 1 Protein, CF

USD :

432 USD

alt names :

EC 3.4.21, EC 3.4.21.35, glandular kallikrein 1, hK1, kallikrein 1, kallikrein 1, renal/pancreas/salivary, kallikrein serine protease 1, kallikrein-1, Kidney/pancreas/salivary gland kallikrein, KLK1, Klk6, KLKR, Tissue kallikrein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage