Recombinant Mouse Active Cathepsin C/DPPI Protein, CF | R&D Systems 2336-CY-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Active Cathepsin C/DPPI Protein, CF

catalog :

2336-CY-010

quantity :

10 ug

price :

503 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Sutton V, Watt S, Akhlaghi H, Cipolla D, Chen K, LaSala D, et al. Pharmacologic inhibition of dipeptidyl peptidase 1 (cathepsin C) does not block in vitro granzyme-mediated target cell killing by CD8 T or NK cells. Front Pharmacol. 2024;15:1396710 pubmed publisher
Chen D, Mirski M, Caton E, Kiser K, Haddaway C, Cetta M, et al. A Breath-Based In Vitro Diagnostics for Lower Respiratory Tract Infection. medRxiv. 2023;: pubmed publisher
Bahuguna A, Khaket T, Bajpai V, Shukla S, Park I, Na M, et al. N-Acetyldopamine dimers from Oxya chinensis sinuosa attenuates lipopolysaccharides induced inflammation and inhibits cathepsin C activity. Comput Struct Biotechnol J. 2022;20:1177-1188 pubmed publisher
Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, et al. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes Dev. 2006;20:543-56 pubmed

product information

brand :

R&D Systems

master code :

2336-CY

SKU :

2336-CY-010

product name :

Recombinant Mouse Active Cathepsin C/DPPI Protein, CF

unit size :

10 ug

seo description :

The Recombinant Mouse Active Cathepsin C/DPPI Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Active Cathepsin C/DPPI Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Cathepsin C/DPPI

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in MES, NaCl and Glycerol.

conjugate :

Unconjugated

dilution :

Enzyme Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

8 kDa and 20-27 kDa, reducing conditions

theoretical molecular weight :

13 kDa (Exclusion domain), 18 kDa (Heavy chain), and 9 kDa (Light chain)

gene symbol :

Ctsc

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Arg-7-amido-4-methylcoumarin (GR-AMC). The specific activity is 60,000 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P97821

applications :

Enzyme Activity

source :

NS0-derived Recombinant Mouse Active Cathepsin C/DPPI Protein, CF

USD :

503 USD

alt names :

cathepsin CEC 3.4.14.1, Cathepsin J, CPPIHMS, CTSC, dipeptidyl peptidase 1, Dipeptidyl peptidase I, Dipeptidyl transferase, dipeptidyl-peptidase I, DPP1, DPPI, DPP-I, JP, JPD, PALS, PLS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage